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COPS7A 抗体 (AA 1-275)

COPS7A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7148498
发货至: 中国
  • 抗原 See all COPS7A 抗体
    COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))
    抗原表位
    • 10
    • 8
    • 6
    • 6
    • 3
    • 2
    • 1
    AA 1-275
    适用
    • 45
    • 22
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 44
    • 1
    克隆类型
    • 45
    多克隆
    标记
    • 17
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COPS7A antibody is un-conjugated
    应用范围
    • 40
    • 21
    • 18
    • 5
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human COP9 signalosome complex subunit 7a protein (1-275AA)
    亚型
    IgG
    Top Product
    Discover our top product COPS7A Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))
    别名
    COPS7A (COPS7A 产品)
    别名
    D6Ertd35e antibody, CSN7A antibody, COP9 signalosome subunit 7A antibody, COPS7A antibody, Cops7a antibody
    背景

    Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

    Aliases: COP9 complex subunit 7a antibody, COP9 constitutive photomorphogenic homolog subunit 7A antibody, COP9 signalosome complex subunit 7a antibody, COP9 signalosome subunit 7A antibody, COPS7A antibody, CSN7A antibody, CSN7A_HUMAN antibody, Dermal papilla derived protein 10 antibody, Dermal papilla-derived protein 10 antibody, DERP10 antibody, JAB1 containing signalosome subunit 7a antibody, JAB1-containing signalosome subunit 7a antibody, SGN7a antibody, Signalosome subunit 7a antibody

    UniProt
    Q9UBW8
    途径
    Cell Division Cycle
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