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COPS7A 抗体 (AA 230-270)

COPS7A 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386939
发货至: 中国
  • 抗原 See all COPS7A 抗体
    COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))
    抗原表位
    • 10
    • 8
    • 6
    • 6
    • 3
    • 2
    • 1
    AA 230-270
    适用
    • 45
    • 21
    • 20
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 44
    • 1
    克隆类型
    • 45
    多克隆
    标记
    • 17
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COPS7A antibody is un-conjugated
    应用范围
    • 39
    • 22
    • 19
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human COPS7A
    亚型
    IgG
    Top Product
    Discover our top product COPS7A Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))
    别名
    COPS7A (COPS7A 产品)
    别名
    D6Ertd35e antibody, CSN7A antibody, COP9 signalosome subunit 7A antibody, COPS7A antibody, Cops7a antibody
    背景

    Synonyms: COP9 signalosome complex subunit 7a, SGN7a, Signalosome subunit 7a, Dermal papilla-derived protein 10, JAB1-containing signalosome subunit 7a, COPS7A, CSN7A, DERP10, CSN7A_HUMAN.

    Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

    基因ID
    50813
    UniProt
    Q9UBW8
    途径
    Cell Division Cycle
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