COPS7B 抗体 (AA 201-264)
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- 抗原 See all COPS7B 抗体
- COPS7B (COP9 Signalosome Complex Subunit 7b (COPS7B))
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抗原表位
- AA 201-264
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COPS7B antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CSN7b
- 亚型
- IgG
- Top Product
- Discover our top product COPS7B Primary Antibody
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anti-COP9 Signalosome Complex Subunit 7b (COPS7B) (AA 1-157) antibody
COPS7B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7b (COPS7B) (AA 61-95) antibodyCOPS7B 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB56230 unconjugated
anti-COP9 Signalosome Complex Subunit 7b (COPS7B) (AA 1-264) antibodyCOPS7B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7b (COPS7B) (AA 223-257) antibodyCOPS7B 适用: 人 WB 宿主: 兔 Polyclonal RB56231 unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- COPS7B (COP9 Signalosome Complex Subunit 7b (COPS7B))
- 别名
- CSN7b (COPS7B 产品)
- 别名
- MGC114836 antibody, D1Wsu66e antibody, E130114M23 antibody, CSN7B antibody, COP9 signalosome subunit 7B antibody, COP9 signalosome subunit 7B S homeolog antibody, Cops7b antibody, COPS7B antibody, cops7b.S antibody
- 背景
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Synonyms: COP9 Complex Homolog Subunit 7b; COP9 Constitutive Photomorphogenic Homolog Subunit 7b; COP9 Signalasome Subunit 7b; COP9 signalosome complex subunit 7b; COPS7B; CSN7B_HUMAN; JAB1 Containing Signalosome Subunit 7b; JAB1-containing signalosome subunit 7b; SGN7b; Signalosome subunit 7b.
Background: The COP9 signalosome (CSN) complex is involved in several different developmental and cellular processes. The complex is made up of several widely expressed proteins: CSN1 (COPS1), CSN2 (COPS2), CSN3 (COPS3), CSN4 (COPS4), CSN5 (COPS5), CSN6 (COP6), CSN7a (COPS7, COPS7a) or CSN7b (COP7b) and CSN8 (COP8). The CSN complex acts as a regulator for the ubiquitin conjugation pathway by mediating the deneddylation of the SCF-type E3 ligase complexes, which leads to a decrease in ubiquitin ligase activity of SCF-complexes. It is also involved in the phosphorylation of p53, c-Jun, I˚Bå and IRF-8, as well as CSN-dependent phosphorylation of p53, and c-Jun protects and promotes degradation by the Ubl system. CSN7 is phosphorylated by CK2 and is composed of two subunits; a and b. CSN7a contains a PCI (Proteasome CSN9 initiation factor 3) region, as well as a coiled-coil region and is predicted to interact with CSN2, CSN3, CSN4, CSN5, CSN6, CSN8, and GPS1. CSN7b contains only a PCI region and is predicted to interact with INT6.
- 途径
- Cell Division Cycle
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