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LRP2 抗体 (C-Term)

LRP2 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5534458
发货至: 中国
  • 抗原 See all LRP2 抗体
    LRP2 (Low Density Lipoprotein Receptor-Related Protein 2 (LRP2))
    抗原表位
    • 16
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 4626-4655, C-Term
    适用
    • 56
    • 32
    • 16
    • 4
    • 4
    宿主
    • 54
    • 2
    克隆类型
    • 54
    • 3
    多克隆
    标记
    • 19
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LRP2 antibody is un-conjugated
    应用范围
    • 22
    • 18
    • 17
    • 13
    • 13
    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    免疫原
    This LRP2 (Megalin) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4626-4655 amino acids from the C-terminal region of human LRP2 (Megalin).
    亚型
    Ig Fraction
    Top Product
    Discover our top product LRP2 Primary Antibody
  • 应用备注
    For IHC-P starting dilution is: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.96 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    LRP2 (Low Density Lipoprotein Receptor-Related Protein 2 (LRP2))
    别名
    LRP2 (LRP2 产品)
    别名
    im:680590 antibody, lrp2 antibody, dbs antibody, gp330 antibody, megalin antibody, DBS antibody, GP330 antibody, AI315343 antibody, AW536255 antibody, D230004K18Rik antibody, Gp330 antibody, Megalin antibody, LDL receptor related protein 2 antibody, low density lipoprotein receptor-related protein 2a antibody, low density lipoprotein receptor-related protein 2 antibody, low-density lipoprotein receptor-related protein 2 antibody, LDL receptor related protein 2 L homeolog antibody, LRP2 antibody, lrp2a antibody, LRP2.3 antibody, lrp2.L antibody, LOC100183506 antibody, lrp2 antibody, Lrp2 antibody
    背景
    Low density lipoprotein (LDL) receptor-related protein (LRP), a member of the LDL receptor family, binds multiple classes of ligands and has been implicated in a broad range of normal and disease processes involving lipid metabolism, protease clearance, and cell migration (1). Structurally, members of the LDLR family share homology within their extracellular domains, which are highlighted by the presence of clusters of ligand-binding repeats. LRP is a large endocytic receptor that participates in several biological pathways and plays prominent roles in lipoprotein metabolism and in the catabolism of proteinases involved in coagulation and fibrinolysis. LRP also mediates the cellular entry of certain viruses and toxins and facilitates the activation of various lysosomal enzymes (2). All LRPs are expressed in the central nervous system and, for most receptors, animal models have shown that they are indispensable for successful neurodevelopment. The mechanisms by which they regulate the formation of the nervous system are varied and include the transduction of extracellular signals and the modulation of intracellular signal propagation, as well as cargo transport, the function most commonly attributed to this gene family (3).
    分子量
    522 kDa
    基因ID
    4036
    UniProt
    P98164
    途径
    Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis, Hormone Transport
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