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- 抗原 See all LRP2 抗体
- LRP2 (Low Density Lipoprotein Receptor-Related Protein 2 (LRP2))
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抗原表位
- AA 4446-4655
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LRP2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB)
- 序列
- FHYRRTGSLL PALPKLPSLS SLVKPSENGN GVTFRSGADL NMDIGVSGFG PETAIDRSMA MSEDFVMEMG KQPIIFENPM YSARDSAVKV VQPIQVTVSE NVDNKNYGSP INPSEIVPET NPTSPAADGT QVTKWNLFKR KSKQTTNFEN PIYAQMENEQ KESVAATPPP SPSLPAKPKP PSRRDPTPTY SATEDTFKDT ANLVKEDSEV
- 交叉反应
- 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 4446-4655 of human LRP2 (NP_004516.2).
- 亚型
- IgG
- Top Product
- Discover our top product LRP2 Primary Antibody
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anti-Low Density Lipoprotein Receptor-Related Protein 2 (LRP2) (AA 3401-3500) antibody
LRP2 适用: 人, 小鼠 ELISA, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 2 (LRP2) (AA 202-332) antibodyLRP2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 2 (LRP2) antibodyLRP2 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 2 (LRP2) (AA 4035-4184) antibodyLRP2 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 2 (LRP2) (AA 1211-1369) antibodyLRP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 2 (LRP2) antibodyLRP2 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 2 (LRP2) (Internal Region) antibodyLRP2 适用: 人, 小鼠, 大鼠 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 2 (LRP2) (AA 4626-4655) antibodyLRP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:200 - 1:1000,IHC,1:20 - 1:100
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- LRP2 (Low Density Lipoprotein Receptor-Related Protein 2 (LRP2))
- 别名
- LRP2 (LRP2 产品)
- 别名
- im:680590 antibody, lrp2 antibody, dbs antibody, gp330 antibody, megalin antibody, DBS antibody, GP330 antibody, AI315343 antibody, AW536255 antibody, D230004K18Rik antibody, Gp330 antibody, Megalin antibody, LDL receptor related protein 2 antibody, low density lipoprotein receptor-related protein 2a antibody, low density lipoprotein receptor-related protein 2 antibody, low-density lipoprotein receptor-related protein 2 antibody, LDL receptor related protein 2 L homeolog antibody, LRP2 antibody, lrp2a antibody, LRP2.3 antibody, lrp2.L antibody, LOC100183506 antibody, lrp2 antibody, Lrp2 antibody
- 背景
- The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling, extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of this membrane receptor is regulated by phosphorylation of its cytoplasmic domain. Mutations in this gene cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR).,LRP2,DBS,GP330,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Lipid Metabolism,Endocrine and metabolic diseases,Obesity,Stem Cells,Cardiovascular,Lipids,Fatty Acids,LRP2
- 分子量
- 521 kDa
- 基因ID
- 4036
- UniProt
- P98164
- 途径
- Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis, Hormone Transport
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