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LRP2 抗体

LRP2 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7238111
发货至: 中国
  • 抗原 See all LRP2 抗体
    LRP2 (Low Density Lipoprotein Receptor-Related Protein 2 (LRP2))
    适用
    • 55
    • 31
    • 15
    • 4
    • 4
    人, 小鼠, 大鼠
    宿主
    • 53
    • 2
    克隆类型
    • 53
    • 3
    多克隆
    标记
    • 18
    • 5
    • 5
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This LRP2 antibody is un-conjugated
    应用范围
    • 21
    • 18
    • 16
    • 13
    • 13
    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Synthetic peptide of human LRP2
    亚型
    IgG
    Top Product
    Discover our top product LRP2 Primary Antibody
  • 应用备注
    IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    LRP2 (Low Density Lipoprotein Receptor-Related Protein 2 (LRP2))
    别名
    LRP2 (LRP2 产品)
    别名
    im:680590 antibody, lrp2 antibody, dbs antibody, gp330 antibody, megalin antibody, DBS antibody, GP330 antibody, AI315343 antibody, AW536255 antibody, D230004K18Rik antibody, Gp330 antibody, Megalin antibody, LDL receptor related protein 2 antibody, low density lipoprotein receptor-related protein 2a antibody, low density lipoprotein receptor-related protein 2 antibody, low-density lipoprotein receptor-related protein 2 antibody, LDL receptor related protein 2 L homeolog antibody, LRP2 antibody, lrp2a antibody, LRP2.3 antibody, lrp2.L antibody, LOC100183506 antibody, lrp2 antibody, Lrp2 antibody
    背景
    The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling, extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of this membrane receptor is regulated by phosphorylation of its cytoplasmic domain. Mutations in this gene cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR).
    NCBI登录号
    NP_004516
    UniProt
    P98164
    途径
    Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis, Hormone Transport
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