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NFKBIB 抗体 (C-Term)

NFKBIB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5534400
发货至: 中国
  • 抗原 See all NFKBIB 抗体
    NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
    抗原表位
    • 30
    • 13
    • 10
    • 10
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 326-355, C-Term
    适用
    • 108
    • 41
    • 35
    • 9
    • 8
    • 8
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    宿主
    • 101
    • 8
    克隆类型
    • 93
    • 16
    多克隆
    标记
    • 55
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This NFKBIB antibody is un-conjugated
    应用范围
    • 81
    • 39
    • 30
    • 24
    • 23
    • 16
    • 13
    • 7
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This NFKBIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-355 amino acids from the C-terminal region of human NFKBIB.
    亚型
    Ig Fraction
    Top Product
    Discover our top product NFKBIB Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.39 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
    别名
    NFKBIB (NFKBIB 产品)
    别名
    NFKBIB antibody, IKB-beta antibody, IKappaBbeta antibody, IkB antibody, IkBb antibody, IKBB antibody, TRIP9 antibody, NFKB inhibitor beta antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta antibody, NFKBIB antibody, Nfkbib antibody
    背景
    NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T, R is an A or G purine, and Y is a C or T pyrimidine).
    分子量
    38 kDa
    基因ID
    4793
    UniProt
    Q15653
    途径
    NF-kappaB Signaling, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
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