NFKBIB 抗体 (AA 56-237)
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北京 101111
Quick Overview for NFKBIB 抗体 (AA 56-237) (ABIN3043567)
抗原
See all NFKBIB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 56-237
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原理
- Anti-IKB beta/NFKBIB Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human IKB beta shares 82%,80% amino acid (aa) sequence identity with mouse,rat IKB beta,respectively.
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产品特性
- Anti-IKB beta/NFKBIB Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human IKB beta recombinant protein (Position: E56-E237). Human IKB beta shares 82% and 80% amino acid (aa) sequence identity with mouse and rat IKB beta, respectively.
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亚型
- IgG
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anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 85-332) antibody
NFKBIB 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (pSer23) antibodyNFKBIB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 1-356) antibodyNFKBIB 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G6 unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 1-356) antibodyNFKBIB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) antibodyNFKBIB 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 56-145) antibodyNFKBIB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) antibodyNFKBIB 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB235 unconjugated Recombinant Antibody
anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 117-345) antibodyNFKBIB 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 1-356) antibodyNFKBIB 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 56-145) antibodyNFKBIB 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B5 unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
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别名
- NFKBIB
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背景
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Background: NF-kappa-B inhibitor beta, also known as IKBB or TRIP9, is a protein that in humans is encoded by the NFKBIB gene. The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. This gene is mapped to 19q13.2. It has been found that in vivo, NFKBIB serves both to inhibit and to facilitate the inflammatory response. NFKBIB degradation releases NF-kappa-B dimers, which upregulate proinflammatory target genes such as TNF-alpha. Surprisingly, absence of NFKBIB results in a dramatic reduction of TNF-alpha in response to lipopolysaccharide, even though activation of NF-kappa-B is normal.
Gene Full Name: NFKB inhibitor beta
Sequence Similarities: Belongs to the NF-kappa-B inhibitor family.
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分子量
- 45-48 kDa
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基因ID
- 4793
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UniProt
- Q15653
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途径
- NF-kappaB Signaling, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
抗原
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