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BAI1 抗体 (C-Term)

BAI1 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5533781
发货至: 中国
  • 抗原 See all BAI1 抗体
    BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))
    抗原表位
    • 15
    • 10
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1537-1567, C-Term
    适用
    • 42
    • 14
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 41
    • 1
    克隆类型
    • 41
    • 1
    多克隆
    标记
    • 22
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BAI1 antibody is un-conjugated
    应用范围
    • 18
    • 15
    • 13
    • 13
    • 13
    • 13
    • 8
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This BAI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1537-1567 amino acids from the C-terminal region of human BAI1.
    亚型
    Ig Fraction
    Top Product
    Discover our top product BAI1 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50

    For FACS starting dilution is: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.32 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))
    别名
    BAI1 (BAI1 产品)
    别名
    BAI1 antibody, GDAIF antibody, B830018M07Rik antibody, R75078 antibody, mKIAA4089 antibody, brain-specific angiogenesis inhibitor 1 antibody, adhesion G protein-coupled receptor B1 antibody, BAI1 antibody, ADGRB1 antibody, LOC100228084 antibody, Adgrb1 antibody
    背景
    Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas.
    分子量
    174 kDa
    基因ID
    575
    UniProt
    O14514
    途径
    p53 Pathway
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