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BAI1 抗体 (AA 691-740)

The 兔 多克隆 anti-BAI1 antibody is suitable to detect BAI1 in samples from 人 和 小鼠. It has been validated for IHC, WB, ELISA 和 IF.
产品编号 ABIN1535650
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BAI1 抗体 (AA 691-740) (ABIN1535650)

抗原

See all BAI1 抗体
BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

适用

  • 49
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  • 1
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  • 1
人, 小鼠

宿主

  • 48
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兔

克隆类型

  • 48
  • 3
多克隆

标记

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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This BAI1 antibody is un-conjugated

应用范围

  • 17
  • 15
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  • 12
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  • 9
  • 5
  • 3
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Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 691-740

    原理

    BAI-1 Antibody

    特异性

    BAI-1 Polyclonal Antibody detects endogenous levels of BAI-1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human BAI1. AA range:691-740

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

    别名

    BAI1

    背景

    Synonyms: BAI1; Brain-specific angiogenesis inhibitor 1

    Background: Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family,

    Gene Name: BAI1

    Protein Name: Brain-specific angiogenesis inhibitor 1

    分子量

    173 kDa

    基因ID

    575

    OMIM

    602682

    UniProt

    O14514

    途径

    p53 Pathway
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