FGFR4 抗体 (Middle Region)
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- 抗原 See all FGFR4 抗体
- FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FGFR4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LITGDSLTSS NDDEDPKSHR DPSNRHSYPQ QAPYWTHPQR MEKKLHAVPA
- 纯化方法
- Affinity purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FGFR4
- Top Product
- Discover our top product FGFR4 Primary Antibody
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anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 22-369) antibody
FGFR4 适用: 人, 猴 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 8A1G2 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 22-369) antibodyFGFR4 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3B5B8 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 24-55), (N-Term) antibodyFGFR4 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB38171 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 24-55) antibodyFGFR4 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 31-145) antibodyFGFR4 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1E2 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) antibodyFGFR4 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) antibodyFGFR4 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 4H2B10B2 unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 1-100) antibodyFGFR4 适用: 人, 大鼠 ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 168-369) antibodyFGFR4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 25-182) antibodyFGFR4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
- 别名
- FGFR4 (FGFR4 产品)
- 别名
- FGFR4 antibody, XFGFR-4 antibody, XFGFR-4a antibody, cd334 antibody, fgfr-4 antibody, jtk2 antibody, tkf antibody, xfgfr4 antibody, CD334 antibody, JTK2 antibody, TKF antibody, Fgfr-4 antibody, etID309818.21 antibody, wu:fc13h10 antibody, zgc:111935 antibody, fgfr-4c antibody, fgfr4 antibody, fibroblast growth factor receptor 4 antibody, fibroblast growth factor receptor 4 S homeolog antibody, FGFR4 antibody, fgfr4 antibody, Fgfr4 antibody, fgfr4.S antibody
- 背景
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The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.
Alias Symbols: TKF, JTK2, CD334
Protein Size: 762 - 基因ID
- 2264
- NCBI登录号
- NM_001291980, NP_002002
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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