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FGFR4 抗体

FGFR4 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 4H2B10B2 unconjugated
产品编号 ABIN969139
发货至: 中国
  • 抗原 See all FGFR4 抗体
    FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
    适用
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    宿主
    • 64
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    小鼠
    克隆类型
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    单克隆
    标记
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    This FGFR4 antibody is un-conjugated
    应用范围
    • 46
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of FGFR4 expressed in E. coli.
    克隆位点
    4H2B10B2
    亚型
    IgG1
    Top Product
    Discover our top product FGFR4 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Ezzat, Zheng, Winer, Asa: "Targeting N-cadherin through fibroblast growth factor receptor-4: distinct pathogenetic and therapeutic implications." in: Molecular endocrinology (Baltimore, Md.), Vol. 20, Issue 11, pp. 2965-75, (2006) (PubMed).

    Angelin: "Telling the liver (not) to make bile acids: a new voice from the gut?" in: Cell metabolism, Vol. 2, Issue 4, pp. 209-10, (2005) (PubMed).

  • 抗原
    FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
    别名
    FGFR4 (FGFR4 产品)
    别名
    FGFR4 antibody, XFGFR-4 antibody, XFGFR-4a antibody, cd334 antibody, fgfr-4 antibody, jtk2 antibody, tkf antibody, xfgfr4 antibody, CD334 antibody, JTK2 antibody, TKF antibody, Fgfr-4 antibody, etID309818.21 antibody, wu:fc13h10 antibody, zgc:111935 antibody, fgfr-4c antibody, fgfr4 antibody, fibroblast growth factor receptor 4 antibody, fibroblast growth factor receptor 4 S homeolog antibody, FGFR4 antibody, fgfr4 antibody, Fgfr4 antibody, fgfr4.S antibody
    背景

    Description: FGFR4 (fibroblast growth factor receptor 4) is part of a family of fibroblast growth factor receptors that mediate the biological functions of specific growth factors. There are four members of the FGF receptor family: FGFR-1 (flg), FGFR-2 (bek, KGFR), FGFR-3 and FGFR-4. Each receptor contains an extracellular ligand binding domain, a transmembrane domain and a cytoplasmic kinase domain. Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues. These receptor proteins play a role in important processes such as cell division, regulating cell growth and maturation, formation of blood vessels, wound healing, and embryo development. Although specific functions of FGFR4 remain unclear, studies indicate that the gene is involved in muscle development and the maturation of bone cells in the skull. FGFR4 may also play a role in the development and maintenance of specialized cells (called foveal cones) in the light-sensitive layer (the retina) at the back of the eye.

    Aliases: TKF, JTK2, CD334, MGC20292

    分子量
    88 kDa
    基因ID
    2264
    HGNC
    2264
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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