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IGF2R 抗体

IGF2R 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal MEM-238 unconjugated
产品编号 ABIN535479
发货至: 中国
  • 抗原 See all IGF2R 抗体
    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
    适用
    • 91
    • 36
    • 19
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    宿主
    • 69
    • 27
    小鼠
    克隆类型
    • 67
    • 29
    单克隆
    标记
    • 49
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IGF2R antibody is un-conjugated
    应用范围
    • 37
    • 37
    • 28
    • 24
    • 16
    • 13
    • 13
    • 12
    • 9
    • 7
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    原理
    Mouse monoclonal antibody raised against recombinant IGF2R.
    特异性
    This antibody recognizes an epitope between domains 2 and 5 of CD222 (IGF2 receptor), a ubiquitously expressed 250 KDa multifunctional type I transmembrane protein.The majority of CD222 is found in the late endosomal/prelysosomal compartment, 5-10 % inthe plasma membrane and the truncated (220 KDa) form of CD222 is present in human and bovine serum.
    交叉反应
    免疫原
    Recombinant protein corresponding to human IGF2R.
    克隆位点
    MEM-238
    亚型
    IgG1
    Top Product
    Discover our top product IGF2R Primary Antibody
  • 应用备注
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    In PBS, pH 7.4 (0.09 % sodium azide)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 4°C. Do not freeze.
    Avoid repeated freezing and thawing.
  • Wood, Hulett: "Cell surface-expressed cation-independent mannose 6-phosphate receptor (CD222) binds enzymatically active heparanase independently of mannose 6-phosphate to promote extracellular matrix degradation." in: The Journal of biological chemistry, Vol. 283, Issue 7, pp. 4165-76, (2008) (PubMed).

    Leksa, Godar, Schiller, Fuertbauer, Muhammad, Slezakova, Horejsi, Steinlein, Weidle, Binder, Stockinger: "TGF-beta-induced apoptosis in endothelial cells mediated by M6P/IGFII-R and mini-plasminogen." in: Journal of cell science, Vol. 118, Issue Pt 19, pp. 4577-86, (2005) (PubMed).

    Gasanov, Koina, Beagley, Aitken, Hansbro: "Identification of the insulin-like growth factor II receptor as a novel receptor for binding and invasion by Listeria monocytogenes." in: Infection and immunity, Vol. 74, Issue 1, pp. 566-77, (2005) (PubMed).

  • 抗原
    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
    别名
    CD222 / IGF2R (IGF2R 产品)
    别名
    CD222 antibody, CIMPR antibody, M6P-R antibody, MPR1 antibody, MPRI antibody, AI661837 antibody, CI-MPR antibody, M6P/IGF2R antibody, Mpr300 antibody, mpri antibody, cd222 antibody, cimpr antibody, m6p-r antibody, insulin like growth factor 2 receptor antibody, insulin-like growth factor 2 receptor antibody, IGF2R antibody, Igf2r antibody, igf2r antibody
    基因ID
    3482
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