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- 抗原 See all IGF2R 抗体
- IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IGF2R antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 原理
- Mouse monoclonal antibody raised against recombinant IGF2R.
- 特异性
- This antibody recognizes an epitope between domains 2 and 5 of CD222 (IGF2 receptor), a ubiquitously expressed 250 KDa multifunctional type I transmembrane protein.The majority of CD222 is found in the late endosomal/prelysosomal compartment, 5-10 % inthe plasma membrane and the truncated (220 KDa) form of CD222 is present in human and bovine serum.
- 交叉反应
- 人
- 免疫原
- Recombinant protein corresponding to human IGF2R.
- 克隆位点
- MEM-238
- 亚型
- IgG1
- Top Product
- Discover our top product IGF2R Primary Antibody
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- 应用备注
- The optimal working dilution should be determined by the end user.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- In PBS, pH 7.4 (0.09 % sodium azide)
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
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Store at 4°C. Do not freeze.
Avoid repeated freezing and thawing.
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Cell surface-expressed cation-independent mannose 6-phosphate receptor (CD222) binds enzymatically active heparanase independently of mannose 6-phosphate to promote extracellular matrix degradation." in: The Journal of biological chemistry, Vol. 283, Issue 7, pp. 4165-76, (2008) (PubMed).
: "TGF-beta-induced apoptosis in endothelial cells mediated by M6P/IGFII-R and mini-plasminogen." in: Journal of cell science, Vol. 118, Issue Pt 19, pp. 4577-86, (2005) (PubMed).
: "Identification of the insulin-like growth factor II receptor as a novel receptor for binding and invasion by Listeria monocytogenes." in: Infection and immunity, Vol. 74, Issue 1, pp. 566-77, (2005) (PubMed).
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Cell surface-expressed cation-independent mannose 6-phosphate receptor (CD222) binds enzymatically active heparanase independently of mannose 6-phosphate to promote extracellular matrix degradation." in: The Journal of biological chemistry, Vol. 283, Issue 7, pp. 4165-76, (2008) (PubMed).
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- 抗原
- IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
- 别名
- CD222 / IGF2R (IGF2R 产品)
- 别名
- CD222 antibody, CIMPR antibody, M6P-R antibody, MPR1 antibody, MPRI antibody, AI661837 antibody, CI-MPR antibody, M6P/IGF2R antibody, Mpr300 antibody, mpri antibody, cd222 antibody, cimpr antibody, m6p-r antibody, insulin like growth factor 2 receptor antibody, insulin-like growth factor 2 receptor antibody, IGF2R antibody, Igf2r antibody, igf2r antibody
- 基因ID
- 3482
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