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IGF2R 抗体 (C-Term)

IGF2R 适用: 人, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044000
发货至: 中国
  • 抗原 See all IGF2R 抗体
    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
    抗原表位
    • 16
    • 13
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2475-2491, C-Term
    适用
    • 90
    • 36
    • 18
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 大鼠
    宿主
    • 68
    • 27
    克隆类型
    • 66
    • 29
    多克隆
    标记
    • 48
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IGF2R antibody is un-conjugated
    应用范围
    • 37
    • 36
    • 28
    • 24
    • 16
    • 13
    • 13
    • 11
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    原理
    Rabbit IgG polyclonal antibody for Cation-independent mannose-6-phosphate receptor(IGF2R) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
    序列
    TKLVSFHDDS DEDLLHI
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Cation-independent mannose-6-phosphate receptor(IGF2R) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
    Gene Name: insulin-like growth factor 2 receptor
    Protein Name: Cation-independent mannose-6-phosphate receptor
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human Mannose 6 Phosphate Receptor(Cation independent)(2475-2491aa TKLVSFHDDSDEDLLHI), different from the related rat and mouse sequences by one amino acid.
    亚型
    IgG
    Top Product
    Discover our top product IGF2R Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • Liang, Hao, Zhang, Wu, Wang: "Insulin-like growth factors in endometrioid adenocarcinoma: correlation with clinico-pathological features and estrogen receptor expression." in: BMC cancer, Vol. 12, pp. 262, (2013) (PubMed).

  • 抗原
    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
    别名
    IGF2R (IGF2R 产品)
    别名
    CD222 antibody, CIMPR antibody, M6P-R antibody, MPR1 antibody, MPRI antibody, AI661837 antibody, CI-MPR antibody, M6P/IGF2R antibody, Mpr300 antibody, mpri antibody, cd222 antibody, cimpr antibody, m6p-r antibody, insulin like growth factor 2 receptor antibody, insulin-like growth factor 2 receptor antibody, IGF2R antibody, Igf2r antibody, igf2r antibody
    背景
    Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

    Synonyms: 300 kDa mannose 6 phosphate receptor antibody|300 kDa mannose 6-phosphate receptor antibody|Cation independent mannose 6 phosphate receptor antibody|Cation-independent mannose-6-phosphate receptor antibody|CD222 antibody|CD222 antigen antibody|CI Man 6 P receptor antibody|CI Man-6-P receptor antibody|CI MPR antibody|CI-MPR antibody|CIMPR antibody|IGF 2 receptor antibody|IGF 2R antibody|IGF II receptor antibody|IGF-II receptor antibody|IGF2 receptor antibody|IGF2R antibody|Insulin like growth factor 2 receptor antibody|Insulin like growth factor II receptor antibody|Insulin-like growth factor 2 receptor antibody|Insulin-like growth factor II receptor antibody|M6P R antibody|M6P/IGF2 receptor antibody|M6P/IGF2R antibody|M6PR antibody|MPR 300 antibody|MPR300 antibody|MPRI antibody|MPRI_HUMAN antibody
    UniProt
    P11717
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