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NFKBIA 抗体 (pTyr42)

NFKBIA 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498722
发货至: 中国
  • 抗原 See all NFKBIA 抗体
    NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
    抗原表位
    • 51
    • 28
    • 23
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    • 16
    • 13
    • 9
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    pTyr42
    适用
    • 244
    • 165
    • 133
    • 28
    • 19
    • 17
    • 14
    • 10
    • 7
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 212
    • 20
    • 7
    • 5
    克隆类型
    • 200
    • 43
    多克隆
    标记
    • 109
    • 20
    • 12
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    This NFKBIA antibody is un-conjugated
    应用范围
    • 173
    • 99
    • 67
    • 66
    • 51
    • 38
    • 33
    • 31
    • 19
    • 16
    • 14
    • 11
    • 4
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    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of IkappaB-alpha protein only when phosphorylated at Tyr42.
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
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    Discover our top product NFKBIA Primary Antibody
  • 应用备注
    Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
    别名
    NFKBIA / IKBA (NFKBIA 产品)
    别名
    IKBA antibody, MAD-3 antibody, NFKBI antibody, AI462015 antibody, Nfkbi antibody, RL/IF-1 antibody, ECI-6/IKBA antibody, NFKBIA antibody, ikbaB antibody, wu:fb81f08 antibody, zgc:56666 antibody, zgc:77616 antibody, ikbaA antibody, wu:fj16a07 antibody, zgc:85769 antibody, NFKB inhibitor alpha antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a antibody, NFKBIA antibody, Nfkbia antibody, nfkbiab antibody, nfkbiaa antibody
    背景
    On the basis of both functional and structural considerations, members of the IkappaB family of proteins can be divided into four groups. The first of these groups, IkappaB-alpha (a 35-37 kDa protein), includes the avian protein pp40 and the mammalian MAD-3, both of which inhibit binding of p50-p65 NFkappaB complex or Rel protein to their cognate binding sites but do not inhibit the binding of p50 homodimer to kappaB sites, suggesting that the IkappaB-alpha family binds to the p65 subunit of p50-p65 heterocomplex through ankyrin repeats. The second member of the IkappaB family is represented by a 45 kDa protein designated IkappaB-beta. The third group of IkappaB proteins is represented by IkappaB-gamma, a 70 kDa protein identical in sequence with the Cterminal domain of the p110 precursor of NFkappaB p50 and expressed predominantly in lymphoid cells.Synonyms: I kappa B-alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF-kappa-B inhibitor alpha, NFKBI
    分子量
    approx. 36 kDa
    基因ID
    4792
    NCBI登录号
    NP_065390
    UniProt
    P25963
    途径
    NF-kappaB Signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Maintenance of Protein Location, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, BCR Signaling
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