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KAP1 抗体 (AA 699-835)

TRIM28 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4952930
发货至: 中国
  • 抗原 See all KAP1 (TRIM28) 抗体
    KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))
    抗原表位
    • 29
    • 15
    • 11
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    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 699-835
    适用
    • 113
    • 53
    • 49
    • 10
    • 9
    • 8
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 114
    • 15
    • 4
    克隆类型
    • 108
    • 25
    多克隆
    标记
    • 62
    • 10
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This KAP1 antibody is un-conjugated
    应用范围
    • 85
    • 41
    • 41
    • 27
    • 26
    • 22
    • 22
    • 21
    • 18
    • 14
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    Amino acids 699-835 of human TRIM28 were used as the immunogen for the TRIM28 antibody.
    亚型
    IgG
    Top Product
    Discover our top product TRIM28 Primary Antibody
  • 应用备注
    Optimal dilution of the TRIM28 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the TRIM28 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))
    别名
    TRIM28 / KAP1 (TRIM28 产品)
    别名
    KAP1 antibody, RNF96 antibody, TF1B antibody, TIF1B antibody, TRIM28 antibody, kap1 antibody, rnf96 antibody, tf1b antibody, tif1b antibody, AA408787 antibody, KAP-1 antibody, KRIP-1 antibody, Tif1b antibody, Tif1beta antibody, Kap1 antibody, Krip1 antibody, TIF1BETA antibody, tripartite motif containing 28 antibody, tripartite motif containing 28 L homeolog antibody, tripartite motif-containing 28 antibody, TRIM28 antibody, trim28.L antibody, Trim28 antibody
    背景
    Tripartite motif-containing 28, also known as transcriptional intermediary factor 1b (TIF1b) and KAP1 (KRAB-associated protein-1), is a protein that in humans is encoded by the TRIM28 gene. The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. KAP1 is a ubiquitously expressed protein involved in many critical functions including: transcriptional regulation, cellular differentiation and proliferation, DNA damage repair, viral suppression, and apoptosis. Its functionality is dependent upon post-translational modifications. Phosphorylation of KAP1 acts as a deactivator of the protein in many of its mechanisms while sumoylation acts as an activator.
    UniProt
    Q13263
    途径
    Hedgehog Signaling, Positive Regulation of Response to DNA Damage Stimulus
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