-
- 抗原 See all MAP2K7 抗体
- MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This MAP2K7 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity
- 免疫原
- Amino acids AASSLEQKLSRLEAKLKQENREARRRIDLNLDISPQRPR of human MAP2K7 were used as the immunogen for the MKK7 antibody.
- 亚型
- IgG
- Top Product
- Discover our top product MAP2K7 Primary Antibody
-
anti-Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) antibody
MAP2K7 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 4-00E-05 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) (AA 1-250) antibodyMAP2K7 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) (AA 1-99) antibodyMAP2K7 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 2G5 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) (AA 113-388) antibodyMAP2K7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) (AA 2-40), (N-Term) antibodyMAP2K7 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) (AA 17-160) antibodyMAP2K7 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) (pSer271) antibodyMAP2K7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) antibodyMAP2K7 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) (Internal Region) antibodyMAP2K7 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) (AA 206-233) antibodyMAP2K7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal dilution of the MKK7 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- 限制
- 仅限研究用
-
- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the MKK7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
- 抗原
- MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))
- 别名
- MEK7 / MAP2K7 / MKK7 (MAP2K7 产品)
- 别名
- MAP2K7 antibody, 2 antibody, JNKK antibody, Jnkk2 antibody, Mapkk7 antibody, Mek7 antibody, Mkk7 antibody, MAPKK7 antibody, MKK7 antibody, PRKMK7 antibody, SAPKK-4 antibody, SAPKK4 antibody, 5930412N11Rik antibody, JNKK 2 antibody, MAPKK 7 antibody, MEK 7 antibody, Prkmk7 antibody, sek2 antibody, si:ch211-254d18.2 antibody, map2k7-A antibody, mitogen-activated protein kinase kinase 7 antibody, mitogen activated protein kinase kinase 7 antibody, mitogen-activated protein kinase kinase 7 L homeolog antibody, MAP2K7 antibody, Map2k7 antibody, map2k7 antibody, map2k7.L antibody
- 背景
- Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K4/MKK4, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3. MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif. MAP2K4/MKK4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue. The monophosphorylation of JNKs on the Thr residue is sufficient to increase JNK activity indicating that MAP2K7/MKK7 is important to trigger JNK activity, while the additional phosphorylation of the Tyr residue by MAP2K4/MKK4 ensures optimal JNK activation. Has a specific role in JNK signal transduction pathway activated by proinflammatory cytokines. The MKK/JNK signaling pathway is also involved in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis. [UniProt]
- UniProt
- O14733
- 途径
- MAPK Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
-
You are here:
