MDM2 抗体 (Ser166)
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- 抗原 See all MDM2 抗体
- MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
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抗原表位
- Ser166
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MDM2 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit polyclonal antibody raised against synthetic peptide of MDM2.
- 序列
- AISET
- 特异性
- MDM2 (Ab-166) Antibody detects endogenous levels of total MDM2 protein.
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Antibody Reactive Against Synthetic Peptide.
- 免疫原
- A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S166 of human MDM2.
- Top Product
- Discover our top product MDM2 Primary Antibody
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- 应用备注
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Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:100-1:200)
The optimal working dilution should be determined by the end user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
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Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 20, pp. 11598-603, (2001) (PubMed).
: "HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation." in: Nature cell biology, Vol. 3, Issue 11, pp. 973-82, (2001) (PubMed).
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A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 20, pp. 11598-603, (2001) (PubMed).
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- 抗原
- MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
- 别名
- MDM2 (MDM2 产品)
- 别名
- ACTFS antibody, HDMX antibody, hdm2 antibody, zgc:109834 antibody, 1700007J15Rik antibody, AA415488 antibody, Mdm-2 antibody, MDM2 proto-oncogene antibody, MDM2 proto-oncogene S homeolog antibody, Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) antibody, MDM2 oncogene, E3 ubiquitin protein ligase antibody, transformed mouse 3T3 cell double minute 2 antibody, MDM2 antibody, mdm2.S antibody, Mdm2 antibody, mdm2 antibody
- 基因ID
- 4193
- 途径
- p53 Pathway, PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Autophagy, Ubiquitin Proteasome Pathway
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