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- 抗原 See all PRKACA 抗体
- PRKACA (Protein Kinase A, alpha (PRKACA))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRKACA antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide of human PRKACA
- 亚型
- IgG
- Top Product
- Discover our top product PRKACA Primary Antibody
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anti-Protein Kinase A, alpha (PRKACA) (N-Term) antibody
PRKACA 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase A, alpha (PRKACA) (Center) antibodyPRKACA 适用: 人, 小鼠 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase A, alpha (PRKACA) (AA 233-351), (Catalytic Subunit alpha) antibodyPRKACA 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase A, alpha (PRKACA) (Internal Region) antibodyPRKACA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase A, alpha (PRKACA) (pThr197) antibodyPRKACA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase A, alpha (PRKACA) (pThr197) antibodyPRKACA 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase A, alpha (PRKACA) (AA 1-120) antibodyPRKACA 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-Protein Kinase A, alpha (PRKACA) (AA 1-120) antibodyPRKACA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7H3A4 unconjugated
anti-Protein Kinase A, alpha (PRKACA) (AA 1-120) antibodyPRKACA 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase A, alpha (PRKACA) (pSer339) antibodyPRKACA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:500 - 1:2000
IHC 1:50 - 1:200 - 说明
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Isoform 1 is ubiquitous, Isoform 2 is sperm-specific and is enriched in pachytene spermatocytes but is not detected in round spermatids
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20C. Avoid freeze / thaw cycles.
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- 抗原
- PRKACA (Protein Kinase A, alpha (PRKACA))
- 别名
- PRKACA (PRKACA 产品)
- 别名
- PKACA antibody, Calpha antibody, Cs-PKA antibody, PKCA1 antibody, PKA antibody, PKCD antibody, Pkaca antibody, zgc:158799 antibody, protein kinase cAMP-activated catalytic subunit alpha antibody, protein kinase, cAMP dependent, catalytic, alpha antibody, cAMP-dependent protein kinase catalytic subunit antibody, protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a antibody, PRKACA antibody, Prkaca antibody, kin-1 antibody, prkacaa antibody
- 背景
- This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. Tissue-specific isoforms that differ at the N-terminus have been described, and these isoforms may differ in the post-translational modifications that occur at the N-terminus of some isoforms.
- 分子量
- 40.59 kDa
- 基因ID
- 5566
- UniProt
- P17612
- 途径
- NF-kappaB Signaling, Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, Lipid Metabolism, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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