SQSTM1 抗体 (C-Term)
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- 抗原 See all SQSTM1 抗体
- SQSTM1 (Sequestosome 1 (SQSTM1))
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抗原表位
- AA 324-353, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SQSTM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- 免疫原
- KLH conjugated synthetic peptide between 324~353 amino acids from the C-terminal region of Human SQSTM1
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SQSTM1 Primary Antibody
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anti-Sequestosome 1 (SQSTM1) antibody
KO Validated SQSTM1 适用: 人 WB, IF, IP, IHC (p), FACS, ICC, PLA 宿主: 兔 Polyclonal unconjugated
anti-Sequestosome 1 (SQSTM1) (AA 51-150) antibodySQSTM1 适用: 人, 小鼠, 大鼠, Cow WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sequestosome 1 (SQSTM1) (AA 1-440) antibodySQSTM1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C11 unconjugated
anti-Sequestosome 1 (SQSTM1) (AA 1-440) antibodySQSTM1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Sequestosome 1 (SQSTM1) (AA 232-356) antibodySQSTM1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5H7E2 unconjugated
anti-Sequestosome 1 (SQSTM1) (AA 317-346) antibodySQSTM1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB4614 unconjugated
anti-Sequestosome 1 (SQSTM1) (AA 136-400) antibodySQSTM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sequestosome 1 (SQSTM1) (C-Term) antibodySQSTM1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sequestosome 1 (SQSTM1) antibodySQSTM1 适用: 人 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 4E2 unconjugated
anti-Sequestosome 1 (SQSTM1) antibodySQSTM1 适用: 人, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 5A2 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- SQSTM1 (Sequestosome 1 (SQSTM1))
- 别名
- SQSTM1 (SQSTM1 产品)
- 别名
- SQSTM1 antibody, sqstm1 antibody, MGC79491 antibody, A170 antibody, OSIL antibody, PDB3 antibody, ZIP3 antibody, p60 antibody, p62 antibody, p62B antibody, OSF-6 antibody, Osi antibody, STAP antibody, ZIP antibody, sb:cb621 antibody, zgc:85784 antibody, sequestosome 1 antibody, sequestosome 1 L homeolog antibody, SQSTM1 antibody, sqstm1 antibody, Sqstm1 antibody, sqstm1.L antibody
- 背景
- SQSTM1/p62 is an adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. This protein may play a role in titin/TTN downstream signaling in muscle cells, and may also regulate signaling cascades through ubiquitination. This protein is involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. SQSTM1/p62 also appears to play a role in macroautophagic removal of intracellular protein aggregates. Cellular depletion studies of SQSTM1/p62 have indicated a role for association with LC3 and aggregate proteins in order to facilitate normal formation of the autophagosome.Synonyms: EBI3-associated protein of 60 kDa, EBIAP, ORCA, OSIL, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Sequestosome-1, Ubiquitin-binding protein p62, p60, p62
- 分子量
- 47687 Da
- 基因ID
- 8878
- NCBI登录号
- NP_001135770
- 途径
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
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