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TRIM29 抗体 (Internal Region)

TRIM29 适用: 人, 小鼠, 大鼠, Cow, 马, Macaque, Chimpanzee WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401461
发货至: 中国
  • 抗原 See all TRIM29 抗体
    TRIM29 (Tripartite Motif Containing 29 (TRIM29))
    抗原表位
    • 24
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 66
    • 9
    • 9
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 马, Macaque, Chimpanzee
    宿主
    • 33
    • 32
    • 1
    克隆类型
    • 36
    • 30
    多克隆
    标记
    • 40
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRIM29 antibody is un-conjugated
    应用范围
    • 39
    • 24
    • 21
    • 18
    • 15
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts with over-expressed, acetylated lysine ATDC protein.
    交叉反应 (详细)
    Species reactivity (expected):Horse, Cattle, Chimpanzee, Macaque, Mouse, Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    免疫原
    Peptide corresponding to an internal portion of human ATDC protein around lysine 116
    亚型
    IgG
    Top Product
    Discover our top product TRIM29 Primary Antibody
  • 应用备注
    ELISA: 1/100,000. Western Blot: 1/500 - 1/3,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.67 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    TRIM29 (Tripartite Motif Containing 29 (TRIM29))
    别名
    TRIM29 / ATDC (TRIM29 产品)
    别名
    ATDC antibody, 1110047J21Rik antibody, 2810431N19Rik antibody, 4732461M22Rik antibody, AI119726 antibody, MGC53484 antibody, TRIM29 antibody, atdc antibody, tripartite motif containing 29 antibody, tripartite motif-containing 29 antibody, tripartite motif containing 29 L homeolog antibody, TRIM29 antibody, Trim29 antibody, trim29.L antibody, trim29 antibody
    背景
    Ataxiatelangiectasia group D-associated protein (ATDC), also called tripartite motif-containing protein 29 (TRIM29), is a novel Histone deacetylase (HDAC) associated protein. Its function is tightly regulated by HDAC. ATDC Lysine 116 (K116) is acetylated and has a significant functional role in regulating cell survival and tumorigenesis. ATDC is expressed in placenta, prostate and thymus, and is over expressed in pancreatic and cervical tumors. Its function in tumor cells is not fully understood. It is constitutively phosphorylated by PKC on serine/threonine in A431 cells. The ATDC gene product is one of a group of proteins that share multiple zinc finger motifs and an adjacent leucine zipper motif. These proteins have been proposed to form homo- or heterodimers involved in nucleic acid binding, consistent with the fact that many of these proteins appear to be transcriptional regulatory factors involved in carcinogenesis and/or differentiation. The likelihood that the ATDC gene product is involved in transcriptional regulation could explain the pleiomorphic characteristics of AT, including abnormal cell cycle regulation.Synonyms: Ataxia-telangiectasia group D-associated protein, Tripartite motif-containing protein 29
    基因ID
    23650
    NCBI登录号
    NP_036233
    UniProt
    Q14134
    途径
    p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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