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WNT1 抗体 (Internal Region)

WNT1 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴, Opossum WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401405
发货至: 中国
  • 抗原 See all WNT1 抗体
    WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
    抗原表位
    • 15
    • 9
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 58
    • 37
    • 11
    • 8
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠, Cow, 犬, 猴, Opossum
    宿主
    • 54
    • 4
    克隆类型
    • 54
    • 4
    多克隆
    标记
    • 33
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WNT1 antibody is un-conjugated
    应用范围
    • 34
    • 22
    • 16
    • 14
    • 14
    • 12
    • 9
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts with Wnt1 protein.
    交叉反应 (详细)
    Species reactivity (expected):Rat, Bovine, Canine, Macaque, Opossum.
    Species reactivity (tested):Human, Mouse.
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    Synthetic peptide corresponding to an internal region of Human Wnt1 protein
    亚型
    IgG
    Top Product
    Discover our top product WNT1 Primary Antibody
  • 应用备注
    ELISA: 1/25,000. Western Blot: 1/1,500 - 1/6,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.38 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
    别名
    WNT1 (WNT1 产品)
    别名
    Xint-1 antibody, Xwnt1 antibody, int-1 antibody, int1 antibody, wnt-1 antibody, wnt1-a antibody, Int-1 antibody, Wnt-1 antibody, sw antibody, swaying antibody, BMND16 antibody, INT1 antibody, OI15 antibody, Int1 antibody, WNT-1 antibody, sb:eu647 antibody, zgc:194464 antibody, zgc:194478 antibody, WNT1 antibody, Wnt family member 1 antibody, Wnt family member 1 L homeolog antibody, wingless-type MMTV integration site family, member 1 antibody, WNT1 antibody, wnt1.L antibody, Wnt1 antibody, wnt1 antibody
    背景
    The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt1 (Wingless-type MMTV integration site family member 1) is a member of the WNT gene family. It is highly conserved in evolution and the protein encoded by this gene is known to be 98 % identical to mouse Wnt1 protein at the amino acid level. Studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. Wnt1 is secreted as an extracellular matrix protein.Synonyms: INT-1, INT1, Proto-oncogene protein Wnt-1
    基因ID
    7471
    NCBI登录号
    NP_005421
    UniProt
    P04628
    途径
    WNT signaling, Dopaminergic Neurogenesis
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