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- 抗原 See all WNT1 抗体
- WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WNT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 大鼠, 绵羊, 犬, Macaque, Opossum (Didelphimorphia)
- 产品特性
- Concentration Definition: by UV absorbance at 280 nm
- 免疫原
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an of human Wnt1 protein.
- 亚型
- IgG
- Top Product
- Discover our top product WNT1 Primary Antibody
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- 应用备注
- This affinity purified antibody has been tested for use in ELISA and western blotting.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.38 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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Wnt pathway activation in long term remnant rat model." in: BioMed research international, Vol. 2014, pp. 324713, (2015) (PubMed).
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Wnt pathway activation in long term remnant rat model." in: BioMed research international, Vol. 2014, pp. 324713, (2015) (PubMed).
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- 抗原
- WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
- 别名
- Wnt1 (WNT1 产品)
- 别名
- Xint-1 antibody, Xwnt1 antibody, int-1 antibody, int1 antibody, wnt-1 antibody, wnt1-a antibody, Int-1 antibody, Wnt-1 antibody, sw antibody, swaying antibody, BMND16 antibody, INT1 antibody, OI15 antibody, Int1 antibody, WNT-1 antibody, sb:eu647 antibody, zgc:194464 antibody, zgc:194478 antibody, WNT1 antibody, Wnt family member 1 antibody, Wnt family member 1 L homeolog antibody, wingless-type MMTV integration site family, member 1 antibody, WNT1 antibody, wnt1.L antibody, Wnt1 antibody, wnt1 antibody
- 背景
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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt1 (Wingless-type MMTV integration site family member 1) is a member of the WNT gene family. It is highly conserved in evolution and the protein encoded by this gene is known to be 98% identical to mouse Wnt1 protein at the amino acid level. Studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. Wnt1 is secreted as an extracellular matrix protein.
Synonyms: INT1 antibody, Murine mammary tumor virus integration site 1 antibody, Oncogene INT1 antibody, Proto oncogene protein Wnt 1 antibody, Wingless type MMTV integration site family member 1 antibody - 基因ID
- 7471, 4885655
- UniProt
- P04628
- 途径
- WNT signaling, Dopaminergic Neurogenesis
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