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WNT1 产品

(Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008].

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Featured WNT1 Categories

WNT1 抗体

High quality antibodies with extensive validation data.

WNT1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

WNT1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended WNT1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
Cat. No. ABIN1683291
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (4)
  • (4)
Cat. No. ABIN733748
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (1)
  • (4)
Cat. No. ABIN6266035
Quantity 100 μL
Datasheet Datasheet

Recommended WNT1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6960531
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971182
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960532
Quantity 96 tests
Datasheet Datasheet

Recommended WNT1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125731
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3075628
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN5509532
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our WNT1 Products

Chen, Zhao, Han, Zhao, Mao, Cui, Chu, Feng, Yin, Wang, Wang, Xu, Zhao: "Wnt1 inhibits vascular smooth muscle cell calcification by promoting ANKH expression." in: Journal of molecular and cellular cardiology, Vol. 135, pp. 10-21, (2020) (PubMed).

Tang, Peng, Huang, Xie, Chen, Shen, Gao, You, Xie, Chen: "Neoisoliquiritigenin Inhibits Tumor Progression by Targeting GRP78-β- catenin Signaling in Breast Cancer." in: Current cancer drug targets, Vol. 18, Issue 4, pp. 390-399, (2018) (PubMed).

Chen, Chen, Wallace, Chen, Yang, Sung, Chiang, Chen, Chua, Yip, Cheng: "Combined therapy with melatonin and exendin-4 effectively attenuated the deterioration of renal function in rat cardiorenal syndrome." in: American journal of translational research, Vol. 9, Issue 2, pp. 214-229, (2017) (PubMed).

Lii, Chang, Chen, Chen, Liu, Yeh, Wang, Liu, Tsai, Li: "Docosahexaenoic acid inhibits 12-O-tetradecanoylphorbol-13- acetate-induced fascin-1-dependent breast cancer cell migration by suppressing the PKCδ- and Wnt-1/β-catenin-mediated pathways." in: Oncotarget, Vol. 7, Issue 18, pp. 25162-79, (2016) (PubMed).

Shan, Lv, Zhao, Liu, Sun, Xi, Xiao, Li: "Wnt/β-catenin pathway is required for epithelial to mesenchymal transition in CXCL12 over expressed breast cancer cells." in: International journal of clinical and experimental pathology, Vol. 8, Issue 10, pp. 12357-67, (2016) (PubMed).

Toffart, Moro-Sibilot, Couraud, Merle, Perol, Girard, Souquet, Mastroianni, Ferretti, Romand, Chatellain, Vesin, Brambilla, Brambilla, Timsit: "Evaluation of RECIST in chemotherapy-treated lung cancer: the Pharmacogenoscan Study." in: BMC cancer, Vol. 14, pp. 989, (2015) (PubMed).

Gao, Yang, Gao, Xu, Niu, Li, Wen: "Salvianolic acid B improves bone marrow-derived mesenchymal stem cell differentiation into alveolar epithelial cells type I via Wnt signaling." in: Molecular medicine reports, Vol. 12, Issue 2, pp. 1971-6, (2015) (PubMed).

Mi, Li, Zhang, Zhao, Peng, Yang, Zheng: "MicroRNA-139-5p regulates C2C12 cell myogenesis through blocking Wnt/β-catenin signaling pathway." in: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 93, Issue 1, pp. 8-15, (2015) (PubMed).

Banon-Maneus, Rovira, Ramirez-Bajo, Moya-Rull, Hierro-Garcia, Takenaka, Diekmann, Eickelberg, Königshoff, Campistol: "Wnt pathway activation in long term remnant rat model." in: BioMed research international, Vol. 2014, pp. 324713, (2015) (PubMed).

Gao, Liu, Chen, Lv, Wu, Mi, Wang: "Comparative study of Hsp27, GSK3?, Wnt1 and PRDX3 in Hirschsprung's disease." in: International journal of experimental pathology, Vol. 95, Issue 3, pp. 229-37, (2014) (PubMed).

Synonyms and alternative names related to WNT1

Wnt family member 1 (WNT1), Wnt family member 1 L homeolog (wnt1.L), wingless-type MMTV integration site family, member 1 (Wnt1), Wnt family member 1 (Wnt1), wingless-type MMTV integration site family, member 1 (wnt1), BMND16, int-1, Int-1, int1, INT1, Int1, OI15, sb:eu647, sw, swaying, wnt-1, Wnt-1, WNT-1, WNT1, wnt1-a, Xint-1, Xwnt1, zgc:194464, zgc:194478

Protein level used designations for WNT1

  • XWnt-1
  • protein Wnt-1
  • proto-oncogene Int-1
  • proto-oncogene Wnt-1
  • proto-oncogene protein Wnt-1
  • proto-oncogene Int-1 homolog
  • wingless-type MMTV integration site family, member 1 (oncogene INT1)
  • Wingless-type MMTV integration site 1 homolog
  • Wingless-type MMTV integration site 1, homolog
  • wingless-related MMTV integration site 1
  • murine mammary tumor virus integration site
  • etID22400.23
  • wingless-type MMTV integration site family member 1
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