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CHEK1 抗体 (AA 258-287)
CHEK1
适用: 人, 小鼠
WB
宿主: 兔
Polyclonal
RB7840
unconjugated
CHEK1抗体详情
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抗原
See all CHEK1 抗体
CHEK1
(Checkpoint Kinase 1 (CHEK1))
抗原表位
All epitopes for CHEK1 抗体
AA 258-287
适用
All reactivities for CHEK1 抗体
人, 小鼠
宿主
All hosts for CHEK1 抗体
兔
克隆类型
All clonalities for CHEK1 抗体
多克隆
标记
All conjugates for CHEK1 抗体
This CHEK1 antibody is un-conjugated
应用范围
All applications for CHEK1 抗体
Western Blotting (WB)
纯化方法
This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This CHK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-287 amino acids from human CHK1.
克隆位点
RB7840
亚型
Ig Fraction
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Discover our top product CHEK1 Primary Antibody
Alternatives
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使用细节
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应用备注
WB: 1:1000
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C.
有效期
6 months
CHEK1目标详情
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抗原
CHEK1
(Checkpoint Kinase 1 (CHEK1))
别名
CHK1 (CHEK1 产品 )
别名
An08g10320 antibody, AO090003000441 antibody, CHK1 antibody, chk1 antibody, C85740 antibody, Chk1 antibody, rad27 antibody, id:ibd2720 antibody, zgc:56093 antibody, CHEK1 antibody, checkpoint kinase 1 antibody, serine/threonine-protein kinase chk1 antibody, serine/threonine-protein kinase Chk1 antibody, CAMK/CAMKL/CHK1 protein kinase Chk1 antibody, checkpoint kinase 1 S homeolog antibody, CHEK1 antibody, ANI_1_2436074 antibody, AOR_1_768154 antibody, PTRG_04183 antibody, SJAG_01680 antibody, PAAG_04978 antibody, MCYG_03290 antibody, VDBG_03742 antibody, chek1.S antibody, Chek1 antibody, chek1 antibody
背景
HRD1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress. Expression of HRD1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum. HRD1 is expressed in many tissues, strongly expressed in brain, pancreas, liver, kidney and skeletal muscle. Amano T, et al. reported that Synoviolin/Hrd1 (expressed in rheumatoid synovium) is a novel causative factor for arthropathy by triggering synovial cell outgrowth through its antiapoptotic effects. HRD1 contains one ring-type zinc finger.
分子量
54434
NCBI登录号
NP_001107593 , NP_001107594 , NP_001231775 , NP_001265
UniProt
O14757
途径
p53 Pathway , Apoptosis , Cell Division Cycle , DNA Damage Repair
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