NR1I2 抗体 (all Isoforms, Internal Region)
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- 抗原 See all NR1I2 抗体
- NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))
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抗原表位
- all Isoforms, Internal Region
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适用
- 人
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This NR1I2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody recognizes PXR / NR1I2. It is expected to recognize all reported isoforms (NP_071285.1, NP_148934.1, NP_003880.3).
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- Affinity Chromatography
- 免疫原
- Peptide with sequence EQFAITLKSYIECNR, from the internal region of the protein sequence
- Top Product
- Discover our top product NR1I2 Primary Antibody
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anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (AA 101-150) antibody
NR1I2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (AA 1-142) antibodyNR1I2 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1D12G1 unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (C-Term) antibodyNR1I2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (AA 1-142) antibodyNR1I2 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 6H11D8 unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (AA 100-127) antibodyNR1I2 适用: 人 WB, FACS, IHC (p), IF 宿主: 兔 Polyclonal RB21890 unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (AA 51-150) antibodyNR1I2 适用: 人, 小鼠, Pig WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (AA 1-434) antibodyNR1I2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (AA 279-378) antibodyNR1I2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) antibodyNR1I2 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (AA 1-434) antibodyNR1I2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Peptide ELISA: 1/4000. Western Blot: 1-3 μg/mL. An additional band of unknown identity was also consistentlyobserved at 35 kDa. This band was successfully blocked by incubation with the immunizingpeptide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, pH ~7.3 containing 0.02 % Sodium Azide and 0.5 % BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))
- 别名
- NR1I2 (NR1I2 产品)
- 别名
- BXR antibody, ONR1 antibody, PAR antibody, PAR1 antibody, PAR2 antibody, PARq antibody, PRR antibody, PXR antibody, SAR antibody, SXR antibody, PXR.1 antibody, PXR.2 antibody, PXR1 antibody, mPXR antibody, bxr antibody, nr1i2 antibody, onr1 antibody, xonr1 antibody, nuclear receptor subfamily 1 group I member 2 antibody, nuclear receptor subfamily 1, group I, member 2 antibody, nuclear receptor subfamily 1 group I member 2 S homeolog antibody, NR1I2 antibody, Nr1i2 antibody, nr1i2.S antibody, nr1i2 antibody
- 背景
- The human nuclear pregnane X receptor (PXR) activates cytochrome P450-3A expression in response to a wide variety of xenobiotics and plays a critical role in mediating dangerous drug-drug interactions. The human PXR is related to the mouse Pxr1, which they had cloned and shown to be activated by dexamethasone, pregnenolone 16-alpha-carbonitrile (PCN), and other compounds known to induce expression of the CYP3A1 gene, the predominant form of CYP3A in rat liver and intestine. Northern blot analysis detected most abundant expression in liver, colon, and small intestine, transcripts of 2.6, 4.3, and 5 kb were present in each of these tissues.Synonyms: Nuclear receptor subfamily 1 group I member 2, Orphan nuclear receptor PAR1, Orphan nuclear receptor PXR, PXR, Pregnane X receptor, Steroid and xenobiotic receptor
- 基因ID
- 8856, 9606
- UniProt
- O75469
- 途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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