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NR1I2 抗体 (AA 51-150)

NR1I2 适用: 人, 小鼠, Pig WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN679598
发货至: 中国
  • 抗原 See all NR1I2 抗体
    NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))
    抗原表位
    • 15
    • 15
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    适用
    • 69
    • 42
    • 28
    • 17
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, Pig
    宿主
    • 75
    • 8
    • 1
    克隆类型
    • 78
    • 6
    多克隆
    标记
    • 38
    • 10
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This NR1I2 antibody is un-conjugated
    应用范围
    • 78
    • 27
    • 19
    • 18
    • 13
    • 13
    • 12
    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, Pig
    预测反应
    Rat,Cow,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human PXR
    亚型
    IgG
    Top Product
    Discover our top product NR1I2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Zhou, Li, Wang, Jin, Shi, Wang, Bi: "Cecropin B Represses CYP3A29 Expression through Activation of the TLR2/4-NF-κB/PXR Signaling Pathway." in: Scientific reports, Vol. 6, pp. 27876, (2016) (PubMed).

    Sehirli, Cetinel, Ozkan, Selman, Tetik, Yuksel, Dulger: "St. John's wort may ameliorate 2,4,6-trinitrobenzenesulfonic acid colitis off rats through the induction of pregnane X receptors and/or P-glycoproteins." in: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, Vol. 66, Issue 2, pp. 203-14, (2015) (PubMed).

  • 抗原
    NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))
    别名
    PXR (NR1I2 产品)
    别名
    BXR antibody, ONR1 antibody, PAR antibody, PAR1 antibody, PAR2 antibody, PARq antibody, PRR antibody, PXR antibody, SAR antibody, SXR antibody, PXR.1 antibody, PXR.2 antibody, PXR1 antibody, mPXR antibody, bxr antibody, nr1i2 antibody, onr1 antibody, xonr1 antibody, nuclear receptor subfamily 1 group I member 2 antibody, nuclear receptor subfamily 1, group I, member 2 antibody, nuclear receptor subfamily 1 group I member 2 S homeolog antibody, NR1I2 antibody, Nr1i2 antibody, nr1i2.S antibody, nr1i2 antibody
    背景

    Synonyms: BXR, PAR, PRR, PXR, SAR, SXR, ONR1, PAR1, PAR2, PARq, Nuclear receptor subfamily 1 group I member 2, Orphan nuclear receptor PAR1, Orphan nuclear receptor PXR, Pregnane X receptor, Steroid and xenobiotic receptor, NR1I2

    Background: Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the antibiotic rifampicin and various plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Response to specific ligands is species-specific. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes.

    基因ID
    8856
    UniProt
    O75469
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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