NR1I2 抗体
(Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))
This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| NR1I2 抗体 (AA 101-150) | 人 | 兔 Polyclonal |
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| NR1I2 抗体 (AA 100-127) | 人 | 兔 Polyclonal |
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| NR1I2 抗体 (AA 1-142) | 人 | 小鼠 Monoclonal |
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| NR1I2 抗体 (AA 1-142) | 人 | 小鼠 Monoclonal |
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| NR1I2 抗体 (AA 7-395) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| NR1I2 抗体 (AA 51-150) | 人 | 兔 Polyclonal |
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| NR1I2 抗体 (C-Term) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| NR1I2 抗体 (AA 1-434) | 人 | 小鼠 Polyclonal |
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| NR1I2 抗体 (AA 108-157) | 人 | 兔 Polyclonal |
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| NR1I2 抗体 (AA 100-200) | 人 | 兔 Polyclonal |
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| NR1I2 抗体 (AA 279-378) | 人 | 小鼠 Polyclonal |
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| NR1I2 抗体 (AA 1-434) | 人 | 兔 Polyclonal |
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| NR1I2 抗体 (Internal Region) | 人 | 山羊 Polyclonal |
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| NR1I2 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| NR1I2 抗体 (C-Term) | 人, 大鼠, Cow, 犬, 豚鼠, Pig, Bat, 猴 | 兔 Polyclonal |
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| NR1I2 抗体 (AA 205-390) | 小鼠 | 兔 Polyclonal |
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| NR1I2 抗体 (AA 175-434) | 人 | 兔 Polyclonal |
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| NR1I2 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| NR1I2 抗体 (AA 51-150) (AbBy Fluor® 680) | 人 | 兔 Polyclonal |
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| NR1I2 抗体 (AA 51-150) (AbBy Fluor® 350) | 人 | 兔 Polyclonal |
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Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- WB (Western Blotting: 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 101-150
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB21890
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 100-127
Primary Antibody
- ELISA (ELISA: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- ICC (Immunocytochemistry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1D12G1
- 标记
- unconjugated
- 抗体亚型
- IgG2b
- 抗原表位
- AA 1-142
Primary Antibody
- ELISA (ELISA: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 6H11D8
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 1-142
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 大鼠, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 7-395
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- FACS (Flow Cytometry: 所列应用)
2 references - 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 51-150
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF/ICC (Immunofluorescence (fixed cells): 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 大鼠, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-434
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 108-157
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 100-200
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 279-378
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IP (Immunoprecipitation: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-434
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 质量等级
- Verified
- 适用
- 人
- 宿主
- 山羊
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Internal Region
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 205-390
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 175-434
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 680
- 抗体亚型
- IgG
- 抗原表位
- AA 51-150
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 350
- 抗体亚型
- IgG
- 抗原表位
- AA 51-150
Latest Publications for our NR1I2 抗体
: "Targeting the PXR-TLR4 signaling pathway to reduce intestinal inflammation in an experimental model of necrotizing enterocolitis." in: Pediatric research, Vol. 83, Issue 5, pp. 1031-1040, (2018) (PubMed).
: "Cecropin B Represses CYP3A29 Expression through Activation of the TLR2/4-NF-κB/PXR Signaling Pathway." in: Scientific reports, Vol. 6, pp. 27876, (2016) (PubMed).
: "St. John's wort may ameliorate 2,4,6-trinitrobenzenesulfonic acid colitis off rats through the induction of pregnane X receptors and/or P-glycoproteins." in: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, Vol. 66, Issue 2, pp. 203-14, (2015) (PubMed).
: "Induced CYP3A4 expression in confluent Huh7 hepatoma cells as a result of decreased cell proliferation and subsequent pregnane X receptor activation." in: Molecular pharmacology, Vol. 83, Issue 3, pp. 659-70, (2013) (PubMed).
: "Chrysin ameliorates chemically induced colitis in the mouse through modulation of a PXR/NF-?B signaling pathway." in: The Journal of pharmacology and experimental therapeutics, Vol. 345, Issue 3, pp. 473-82, (2013) (PubMed).
: "A nuclear receptor-like pathway regulating multidrug resistance in fungi." in: Nature, Vol. 452, Issue 7187, pp. 604-9, (2008) (PubMed).
: "Cecropin B Represses CYP3A29 Expression through Activation of the TLR2/4-NF-κB/PXR Signaling Pathway." in: Scientific reports, Vol. 6, pp. 27876, (2016) (PubMed).
: "St. John's wort may ameliorate 2,4,6-trinitrobenzenesulfonic acid colitis off rats through the induction of pregnane X receptors and/or P-glycoproteins." in: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, Vol. 66, Issue 2, pp. 203-14, (2015) (PubMed).
: "Induced CYP3A4 expression in confluent Huh7 hepatoma cells as a result of decreased cell proliferation and subsequent pregnane X receptor activation." in: Molecular pharmacology, Vol. 83, Issue 3, pp. 659-70, (2013) (PubMed).
: "Chrysin ameliorates chemically induced colitis in the mouse through modulation of a PXR/NF-?B signaling pathway." in: The Journal of pharmacology and experimental therapeutics, Vol. 345, Issue 3, pp. 473-82, (2013) (PubMed).
: "A nuclear receptor-like pathway regulating multidrug resistance in fungi." in: Nature, Vol. 452, Issue 7187, pp. 604-9, (2008) (PubMed).
Aliases for NR1I2 抗体
nuclear receptor subfamily 1 group I member 2 (NR1I2) 抗体nuclear receptor subfamily 1, group I, member 2 (Nr1i2) 抗体
nuclear receptor subfamily 1 group I member 2 (Nr1i2) 抗体
nuclear receptor subfamily 1 group I member 2 S homeolog (nr1i2.S) 抗体
nuclear receptor subfamily 1, group I, member 2 (nr1i2) 抗体
BXR 抗体
bxr 抗体
mPXR 抗体
nr1i2 抗体
ONR1 抗体
onr1 抗体
PAR 抗体
PAR1 抗体
PAR2 抗体
PARq 抗体
PRR 抗体
PXR 抗体
PXR.1 抗体
PXR.2 抗体
PXR1 抗体
SAR 抗体
SXR 抗体
xonr1 抗体
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