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NR1I2 抗体

NR1I2 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7259534
发货至: 中国
  • 抗原 See all NR1I2 抗体
    NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))
    适用
    • 69
    • 42
    • 27
    • 18
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 75
    • 8
    • 1
    克隆类型
    • 78
    • 6
    多克隆
    标记
    • 38
    • 10
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This NR1I2 antibody is un-conjugated
    应用范围
    • 78
    • 28
    • 19
    • 19
    • 13
    • 13
    • 13
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human PXR
    亚型
    IgG
    Top Product
    Discover our top product NR1I2 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))
    别名
    PXR (NR1I2 产品)
    别名
    BXR antibody, ONR1 antibody, PAR antibody, PAR1 antibody, PAR2 antibody, PARq antibody, PRR antibody, PXR antibody, SAR antibody, SXR antibody, PXR.1 antibody, PXR.2 antibody, PXR1 antibody, mPXR antibody, bxr antibody, nr1i2 antibody, onr1 antibody, xonr1 antibody, nuclear receptor subfamily 1 group I member 2 antibody, nuclear receptor subfamily 1, group I, member 2 antibody, nuclear receptor subfamily 1 group I member 2 S homeolog antibody, NR1I2 antibody, Nr1i2 antibody, nr1i2.S antibody, nr1i2 antibody
    背景
    This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.
    分子量

    Observed_MW: 50 kDa

    Calculated_MW: 50 kDa

    基因ID
    8856
    UniProt
    O75469
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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