Cytohesin 2 抗体 (N-Term)
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- 抗原 See all Cytohesin 2 (CYTH2) 抗体
- Cytohesin 2 (CYTH2)
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抗原表位
- N-Term
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适用
- 人, 大鼠, 小鼠, 犬
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This Cytohesin 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody reacts to ARNO / cytohesin 2.
- 交叉反应 （详细）
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Species reactivity (expected):Mouse, Canine.
Species reactivity (tested):Human, Rat. - 纯化方法
- Affinity chromatography
- 免疫原
- Peptide with sequence EDGVYEPPDLTP-C, from the N Terminus of the protein sequence
- Top Product
- Discover our top product CYTH2 Primary Antibody
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anti-Cytohesin 2 (CYTH2) (AA 314-398) antibody
CYTH2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6H5 unconjugated
anti-Cytohesin 2 (CYTH2) (AA 1-390) antibodyCYTH2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytohesin 2 (CYTH2) (AA 150-350) antibodyCYTH2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytohesin 2 (CYTH2) (AA 1-400) antibodyCYTH2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Cytohesin 2 (CYTH2) antibodyCYTH2 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Cytohesin 2 (CYTH2) (AA 314-398) antibodyCYTH2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5E11 unconjugated
anti-Cytohesin 2 (CYTH2) (N-Term) antibodyVerified CYTH2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- Peptide ELISA: 1/32000. Western Blot: 0.5 - 1.5 μg/mL.
- 限制
- 仅限研究用
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- 浓度
- 0,5 mg/mL
- 缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Cytohesin 2 (CYTH2)
- 别名
- Cytohesin 2 (CYTH2 产品)
- 别名
- ARNO antibody, CTS18 antibody, CTS18.1 antibody, PSCD2 antibody, PSCD2L antibody, SEC7L antibody, Sec7p-L antibody, Sec7p-like antibody, CLM2 antibody, Pscd2 antibody, Arno antibody, Sec7 antibody, Sec7B antibody, pscd2 antibody, MGC84366 antibody, CYTH2 antibody, cyth2 antibody, cytohesin 2 antibody, cytohesin-2 antibody, cytohesin 2 L homeolog antibody, si:dkey-283b15.4 antibody, CYTH2 antibody, PTRG_08834 antibody, Cyth2 antibody, cyth2.L antibody, cyth2 antibody, si:dkey-283b15.4 antibody
- 背景
- The ADP-ribosylation factor (Arf) family comprises a group of structurally and functionally conserved 21 kDa proteins, which are members of the Ras superfamily of regulatory GTP-binding proteins. Arf is involved in intracellular protein traffic to and within the Golgi complex. Arf has a number of disparate activities including maintenance of organelle integrity, assembly of coat proteins, as a co-factor for cholera toxin and as an activator of phospholipase D. Like other small GTPases, Arf is found to be active when bound to GTP and inactive when bound to GDP. Arf's activation is dependent upon guanine nucleotide exchange factors (GEFs) which increase the rate of exchange of bound GDP with GTP. All GEFs have a highly conserved Sec7 domain. GEF activity lies in the Sec7 domain and this activity has been shown to be inhibited by the fungal metabolite brefeldin-A (BFA). A small group of GEFs which are insensitive to brefeldin-A (BFA) include cytohesin-1 (B2-1), cytohesin-2 (ARNO), cytohesin-3 (ARNO3), and cytohesin-4. All cytohesins function in the cell periphery and contain a pleckstrin homology (PH) domain. The PH domain has been shown to interact with phosphatidylinositol 3,4,5-triphosphate and is believed to promote membrane targeting of the cytohesins. Recruitment of the cytohesins to the membranes can occur in response to tyrosine kinase receptor activation. This response appears to require the activation of phosphatidylinositol 3-kinase (PI 3-kinase).Synonyms: ARF exchange factor, ARF nucleotide-binding site opener, ARNO, CYTH2, PH, PSCD2, PSCD2L, SEC7 and coiled-coil domain-containing protein 2
- 基因ID
- 9266, 9606
- UniProt
- Q99418
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