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Cytohesin 2 产品

(Cytohesin 2 (CYTH2))

Categories

The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].

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Featured Cytohesin 2 Categories

Cytohesin 2 抗体

High quality antibodies with extensive validation data.

Cytohesin 2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Cytohesin 2 抗体

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Reactivity Human
Application WB, ELISA, IF, IHC (p)
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Cat. No. ABIN564002
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Reactivity Human
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Cat. No. ABIN7443044
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Cat. No. ABIN7149288
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Recommended Cytohesin 2 蛋白

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Cat. No. ABIN7122587
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Cat. No. ABIN1351036
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Cat. No. ABIN1351038
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Latest Publications for our Cytohesin 2 Products

Mannell, Pircher, Chaudhry, Alig, Koch, Mettler, Pohl, Krötz: "ARNO regulates VEGF-dependent tissue responses by stabilizing endothelial VEGFR-2 surface expression." in: Cardiovascular research, Vol. 93, Issue 1, pp. 111-9, (2011) (PubMed).

Kolanus: "Guanine nucleotide exchange factors of the cytohesin family and their roles in signal transduction." in: Immunological reviews, Vol. 218, pp. 102-13, (2007) (PubMed).

Synonyms and alternative names related to Cytohesin 2

cytohesin 2 (CYTH2), cytohesin-2 (PTRG_08834), cytohesin 2 (Cyth2), cytohesin 2 L homeolog (cyth2.L), cytohesin 2 (cyth2), si:dkey-283b15.4 (si:dkey-283b15.4), ARNO, Arno, CLM2, CTS18, CTS18.1, CYTH2, cyth2, MGC84366, PSCD2, Pscd2, pscd2, PSCD2L, Sec7, Sec7B, SEC7L, Sec7p-L, Sec7p-like

Protein level used designations for Cytohesin 2

  • ARF exchange factor
  • ARF nucleotide-binding site opener
  • PH, SEC7 and coiled-coil domain-containing protein 2
  • cytohesin-2
  • pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2)
  • pleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2)
  • SEC7 homolog B
  • mSec7-2
  • pleckstrin homology, Sec7 and coiled-coil domains 2
  • ARF nucleotide binding site opener
  • CLM2
  • cytohesin 2
  • pleckstrin homology, Sec7 and coiled/coil domains 2
  • cytohesin-2-like
  • LOW QUALITY PROTEIN: cytohesin-2
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