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XRCC6 抗体 (N-Term)

Name: XRCC6 抗体 (N-Term)
SKU: ABIN374763
Availability: OutOfStock

XRCC6 适用: 人 WB 宿主: 山羊 Polyclonal unconjugated

Image no. 2 for anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (N-Term) antibody (ABIN374763) (XRCC6 抗体 (N-Term))

Image no. 1 for anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (N-Term) antibody (ABIN374763) (XRCC6 抗体 (N-Term))

2 images

产品编号 ABIN374763

发货至: 中国

Datasheet as PDF

抗原 See all XRCC6 抗体

XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
抗原表位
13

9

8

8

8

8

7

6

6

6

4

4

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
144

40

24

9

2

2

1

1

1

1

1

1

1

1
人
宿主
124

21

2
山羊
Compatible Secondaries
克隆类型
115

31
多克隆
标记
95

8

8

7

6

5

3

3

3

3

3

3
This XRCC6 antibody is un-conjugated
应用范围
117

78

73

52

46

24

22

15

4

2

2

2

2

1

1
Western Blotting (WB)

特异性

This antibody reacts to KU70 / XRCC6.

纯化方法

Affinity chromatography

免疫原

Peptide with sequence YKTEGDEEAEEEQ-C, from the N Terminus of the protein sequence

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anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 319-538) antibody
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anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) antibody
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anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (Ser404) antibody
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anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (acLys542) antibody
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anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 408-609) antibody
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anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 6-214) antibody
XRCC6 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 2F7F5 unconjugated

应用备注

Peptide ELISA: 1/2000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

0.5 mg/mL

缓冲液

Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

别名

XRCC6 / Ku70 (XRCC6 产品)

别名

CTC75 antibody, CTCBF antibody, G22P1 antibody, KU70 antibody, ML8 antibody, TLAA antibody, 70kDa antibody, G22p1 antibody, Ku70 antibody, Kup70 antibody, X-ray repair cross complementing 6 antibody, ATP-dependent DNA helicase II, 70 kDa subunit antibody, X-ray repair complementing defective repair in Chinese hamster cells 6 L homeolog antibody, X-ray repair complementing defective repair in Chinese hamster cells 6 antibody, XRCC6 antibody, Bm1_41430 antibody, xrcc6.L antibody, Xrcc6 antibody

背景

Ku70 heterodimerises with Ku80 to form the ATP-dependent DNA helicase II, a single stranded helicase that binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. The heterodimer plays a role in non-homologous end-joining (NHEJ) required for double-strand break repair and V(D)J recombination. It acts as the regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit (PRKDC) for DNA. The Ku70/80 heterodimer is also required for osteocalcin gene expression.Synonyms: 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, DNA repair protein XRCC6, G22P1, Lupus Ku autoantigen protein p70, TLAA, Thyroid-lupus autoantigen

基因ID

2547, 9606

UniProt

P12956

途径

DNA Damage Repair