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XRCC6 抗体 (C-Term)

Name: XRCC6 抗体 (C-Term)
Brand: antibodies-online
SKU: ABIN2855186
Availability: OutOfStock

XRCC6 适用: 人 WB, IF, IHC (p), IP, ICC, PLA 宿主: 兔 Polyclonal unconjugated

WB Image Ku70 antibody detects Ku70 protein by western blot analysis. (XRCC6 抗体 (C-Term))

IP Image Ku70 antibody immunoprecipitates Ku70 protein in IP experiments. (XRCC6 抗体 (C-Term))

IHC-P Image Ku70 antibody detects Ku70 protein at nucleus in human cervical cancer by immunohistochemical analysis. (XRCC6 抗体 (C-Term))

IHC

IHC-P Image Immunohistochemical analysis of paraffin-embedded D54 xenograft, using Ku70, antibody at 1:500 dilution. (XRCC6 抗体 (C-Term))

IHC

ICC/IF Image Ku70 antibody detects Ku70 protein at nucleus by immunofluorescent analysis. (XRCC6 抗体 (C-Term))

SF-1 controls centrosome homeostasis independent of its DNA binding domain. (XRCC6 抗体 (C-Term))

6 images

(1 reference)

产品编号 ABIN2855186

发货至: 中国

Datasheet as PDF

抗原 See all XRCC6 抗体

XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
抗原表位
12

9

8

8

8

8

7

6

6

6

4

4

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
143

40

24

9

2

2

1

1

1

1

1

1

1

1
人
宿主
123

21

2
兔
Compatible Secondaries
克隆类型
114

31
多克隆
标记
94

8

8

7

6

5

3

3

3

3

3

3
This XRCC6 antibody is un-conjugated
应用范围
116

78

73

51

46

23

21

14

4

2

2

2

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC), Proximity Ligation Assay (PLA)

交叉反应

人, 小鼠

产品特性

Rabbit Polyclonal antibody to Ku70 (X-ray repair complementing defective repair in Chinese hamster cells 6)
Ku70 antibody

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Recombinant protein encompassing a sequence within the C-terminus region of human Ku70. The exact sequence is proprietary.

亚型

IgG

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XRCC6 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4C2-1A6 unconjugated

anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 500-600) antibody
XRCC6 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 319-538) antibody
XRCC6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 397-603) antibody
XRCC6 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) antibody
XRCC6 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (Ser404) antibody
XRCC6 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (acLys542) antibody
XRCC6 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 408-609) antibody
XRCC6 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 6-214) antibody
XRCC6 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 2F7F5 unconjugated

anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 521-548), (C-Term) antibody
XRCC6 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB20806 unconjugated

应用备注

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:500-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

说明

Positive Control: 293T , A431 , HeLa , HepG2

限制

仅限研究用
状态

Liquid

浓度

0.25 mg/mL

缓冲液

1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Chakraborty, Tapryal, Venkova, Horikoshi, Pandita, Sarker, Sarkar, Pandita, Hazra: "Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes." in: Nature communications, Vol. 7, pp. 13049, (2018) (PubMed).
抗原

XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

别名

X-ray repair cross complementing 6 (XRCC6 产品)

别名

CTC75 antibody, CTCBF antibody, G22P1 antibody, KU70 antibody, ML8 antibody, TLAA antibody, 70kDa antibody, G22p1 antibody, Ku70 antibody, Kup70 antibody, X-ray repair cross complementing 6 antibody, ATP-dependent DNA helicase II, 70 kDa subunit antibody, X-ray repair complementing defective repair in Chinese hamster cells 6 L homeolog antibody, X-ray repair complementing defective repair in Chinese hamster cells 6 antibody, XRCC6 antibody, Bm1_41430 antibody, xrcc6.L antibody, Xrcc6 antibody

背景

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Cellular Localization: Nucleus

分子量

70 kDa

基因ID

2547

UniProt

P12956

途径

DNA Damage Repair