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产品编号 ABIN1513143
发货至: 中国
  • 抗原 See all XRCC6 抗体
    XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
    抗原表位
    • 13
    • 9
    • 8
    • 8
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 4
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    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 500-600
    适用
    • 143
    • 40
    • 24
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 123
    • 21
    • 2
    克隆类型
    • 114
    • 31
    多克隆
    标记
    • 94
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This XRCC6 antibody is un-conjugated
    应用范围
    • 116
    • 78
    • 72
    • 51
    • 46
    • 24
    • 22
    • 15
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    序列
    PEQAVDLTLP KVEAMNKRLG SLVDEFKELV YPPDYNPEGK VTKRKHDNEG SGSKRPKVEY SEEELKTHIS KGTLGKFTVP MLKEACRAYG LKSGLKKQEL L
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 500-600 of human Ku70 (NP_001460.1).
    亚型
    IgG
    Top Product
    Discover our top product XRCC6 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Li, Zhang, Chen, Guo, Zhang, Tang, Xu, Zhang, Tao, Wang, Jiang, Sun, Mao: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).

  • 抗原
    XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
    别名
    XRCC6 (XRCC6 产品)
    别名
    CTC75 antibody, CTCBF antibody, G22P1 antibody, KU70 antibody, ML8 antibody, TLAA antibody, 70kDa antibody, G22p1 antibody, Ku70 antibody, Kup70 antibody, X-ray repair cross complementing 6 antibody, ATP-dependent DNA helicase II, 70 kDa subunit antibody, X-ray repair complementing defective repair in Chinese hamster cells 6 L homeolog antibody, X-ray repair complementing defective repair in Chinese hamster cells 6 antibody, XRCC6 antibody, Bm1_41430 antibody, xrcc6.L antibody, Xrcc6 antibody
    背景
    The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.,XRCC6,CTC75,CTCBF,G22P1,KU70,ML8,TLAA,Epigenetics & Nuclear Signaling,DNA Damage & Repair,RNA Binding,Cancer,Cell Biology & Developmental Biology,Cell Cycle,XRCC6
    分子量
    65 kDa/69 kDa
    基因ID
    2547
    UniProt
    P12956
    途径
    DNA Damage Repair
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