LEF1 抗体 (Internal Region)
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- 抗原 See all LEF1 抗体
- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠, 犬
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This LEF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody reacts to LEF1.
- 交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography
- 免疫原
- Peptide with sequence C-QHEQRKEQEPKRPH, from the internal region of the protein sequence
- Top Product
- Discover our top product LEF1 Primary Antibody
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anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 100-399) antibody
LEF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 331-399) antibodyLEF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 1-399) antibodyLEF1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3H5 unconjugated
anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (Internal Region) antibodyVerified LEF1 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 33-138) antibodyLEF1 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 1A4B11 unconjugated
anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 14-123) antibodyLEF1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5A3 unconjugated
anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 75-216) antibodyLEF1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 33-138) antibodyLEF1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A8 unconjugated
anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 10-37), (N-Term) antibodyLEF1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB31989 unconjugated
anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (Internal Region) antibodyLEF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Peptide ELISA: 1/32000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
- 别名
- LEF1 (LEF1 产品)
- 别名
- LEF1 antibody, 3000002B05 antibody, AI451430 antibody, Lef-1 antibody, LEF-1 antibody, TCF10 antibody, TCF1ALPHA antibody, TCF7L3 antibody, lymphoid enhancer binding factor 1 antibody, lymphoid enhancer-binding factor 1 antibody, lymphoid enhancer factor XLEF-1B antibody, LEF1 antibody, lef1 antibody, Lef1 antibody
- 背景
- Lymphoid enhancer factor, LEF1, is a transcription factor of the High Mobility Group of DNA binding proteins. It is one member of a family of four proteins referred to as LEF/TCF transcription factors (LEF1, TCF1, TCF3 and TCF4). These factors play crucial roles in WNT/Wingless signaling, a signal transduction cascade that directs cell differentiation. Aberrant activation of the WNT/Wingless pathway is also a root cause in the genesis of certain cancers such as colon cancer, melanoma and breast cancer. LEF1 is expressed during development in many different differentiating tissues, and in a few tissues after birth. LEF1 expression is required for proper development of breast, teeth, hair, whiskers and the trigeminal nerve. It is redundant with TCF1 (for T cell Factor 1) for correct development of T lymphocytes in the thymus. LEF1 is a 399 amino acid protein. Alternative splice forms of LEF1 and other LEF/TCF family members have been identified, but the expression pattern and relative abundance of these alternative forms have not been well studied. They can appear on immunoblots as small immunoreactive forms.Synonyms: LEF-1, Lymphoid enhancer-binding factor 1, T cell-specific transcription factor 1-alpha, TCF1-alpha
- 基因ID
- 51176
- NCBI登录号
- NP_001124185
- UniProt
- Q9UJU2
- 途径
- WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding
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