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LEF1 抗体 (N-Term)

Name: LEF1 抗体 (N-Term)
SKU: ABIN655987
Availability: OutOfStock

LEF1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB31989 unconjugated

Anti-LEF1 Antibody (N-term) at 1:2000 dilution + Jurkat whole cell lysate Lysates/proteins at 20 μg per lane. (LEF1 抗体 (N-Term))

LEF1 Antibody (N-term) (ABIN655987 and ABIN2845371) western blot analysis in MDA-M cell line lysates (35 μg/lane). (LEF1 抗体 (N-Term))

Fluorescent confocal image of A431 cell stained with LEF1 Antibody (N-term) (ABIN655987 and ABIN2845371). (LEF1 抗体 (N-Term))

4 images

(1 reference)

产品编号 ABIN655987

发货至: 中国

Datasheet as PDF

抗原 See all LEF1 抗体

LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
抗原表位
10

8

7

6

5

4

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 10-37, N-Term
适用
80

20

13

7

7

6

4

4

4

4

3

3

2

1

1
人
宿主
52

24

4

1
兔
Compatible Secondaries
克隆类型
54

27
多克隆
标记
61

4

3

3

2

2

1

1

1

1

1

1
This LEF1 antibody is un-conjugated
应用范围
68

35

13

10

7

6

5

3

2

2

2

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF)

预测反应

M, Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This LEF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-37 amino acids from the N-terminal region of human LEF1.

克隆位点

RB31989

亚型

Ig Fraction

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anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 331-399) antibody
LEF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 1-399) antibody
LEF1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3H5 unconjugated

anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (Internal Region) antibody
Verified LEF1 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 33-138) antibody
LEF1 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 1A4B11 unconjugated

anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 14-123) antibody
LEF1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5A3 unconjugated

anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 75-216) antibody
LEF1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 33-138) antibody
LEF1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A8 unconjugated

anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (Internal Region) antibody
LEF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Lymphoid Enhancer-Binding Factor 1 (LEF1) (AA 51-100) antibody
LEF1 适用: 人, 犬, Cow, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:10~50. WB: 1:2000. WB: 1:2000. WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Yao, Li, Liang, Lu, Zhu, Liu, Zhang, Yuan, Wang: "Methylprednisolone suppresses the Wnt signaling pathway in chronic lymphocytic leukemia cell line MEC-1 regulated by LEF-1 expression." in: International journal of clinical and experimental pathology, Vol. 8, Issue 7, pp. 7921-8, (2015) (PubMed).
抗原

LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

别名

LEF1 (LEF1 产品)

别名

LEF1 antibody, 3000002B05 antibody, AI451430 antibody, Lef-1 antibody, LEF-1 antibody, TCF10 antibody, TCF1ALPHA antibody, TCF7L3 antibody, lymphoid enhancer binding factor 1 antibody, lymphoid enhancer-binding factor 1 antibody, lymphoid enhancer factor XLEF-1B antibody, LEF1 antibody, lef1 antibody, Lef1 antibody

背景

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

分子量

44201

基因ID

51176

NCBI登录号

NP_001124185, NP_001124186, NP_001159591, NP_057353

UniProt

Q9UJU2

途径

WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding