LEF1 抗体
(Lymphoid Enhancer-Binding Factor 1 (LEF1))
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| LEF1 抗体 (AA 100-399) | 人 | 兔 Polyclonal |
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| LEF1 抗体 (AA 331-399) | 人 | 兔 Polyclonal |
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| LEF1 抗体 (AA 1-399) | 人 | 小鼠 Monoclonal |
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| LEF1 抗体 (AA 33-138) | 人 | 小鼠 Monoclonal |
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| LEF1 抗体 (Internal Region) | 人 | 山羊 Polyclonal |
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| LEF1 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| LEF1 抗体 (AA 14-123) | 人 | 小鼠 Monoclonal |
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| LEF1 抗体 (AA 75-216) | 人 | 兔 Polyclonal |
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| LEF1 抗体 (AA 33-138) | 人 | 小鼠 Monoclonal |
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| LEF1 抗体 (AA 51-100) | 人, 犬, 豚鼠, Cow, 猴 | 兔 Polyclonal |
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| LEF1 抗体 (pSer42) | 人 | 兔 Polyclonal |
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| LEF1 抗体 (AA 282-331) | 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 山羊, 兔, 马, Pig, 斑马鱼, 小鸡, 猴, Bat, 非洲爪蟾 | 兔 Polyclonal |
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| LEF1 抗体 (AA 10-37) | 人 | 小鼠 Monoclonal |
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| LEF1 抗体 (Internal Region) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| LEF1 抗体 (AA 33-138) | 人 | 小鼠 Monoclonal |
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| LEF1 抗体 (AA 14-123) | 人 | 小鼠 Monoclonal |
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| LEF1 抗体 (AA 95-283) | 人 | 小鼠 Monoclonal |
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| LEF1 抗体 (AA 72-121) | 人, 小鼠, 豚鼠, 马, Pig, 猴 | 兔 Polyclonal |
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| LEF1 抗体 | 人 | 兔 Monoclonal |
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| LEF1 抗体 (pSer42) | 人 | 兔 Polyclonal |
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Primary Antibody
- CUT&RUN (Cleavage Under Targets and Release Using Nuclease: 已在此应用中经过独立验证)
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IP (Immunoprecipitation: 有验证图片)
3 references - 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 100-399
Independently Validated
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- SDS (SDS-PAGE: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 331-399
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- RNAi (RNA Interference: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 3H5
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 1-399
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1A4B11
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 33-138
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 质量等级
- Verified
- 适用
- 人
- 宿主
- 山羊
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Internal Region
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB31989
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 10-37, N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 5A3
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 14-123
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 75-216
Primary Antibody
- ELISA (ELISA: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1A8
- 标记
- unconjugated
- 抗体亚型
- IgG2a
- 抗原表位
- AA 33-138
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- WB (Western Blotting: 所列应用)
- 适用
- 人, 犬, 豚鼠, Cow, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 51-100
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pSer42
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 山羊, 兔, 马, Pig, 斑马鱼, 小鸡, 猴, Bat, 非洲爪蟾
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 282-331
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 661CT8-3-5
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 10-37
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Internal Region
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2E2
- 标记
- unconjugated
- 抗体亚型
- IgG2b
- 抗原表位
- AA 33-138
Primary Antibody
- ELISA (ELISA: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 6H3
- 标记
- unconjugated
- 抗体亚型
- IgG2a
- 抗原表位
- AA 14-123
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1866CT561-78-3
- 标记
- unconjugated
- 抗体亚型
- IgG1 kappa
- 抗原表位
- AA 95-283
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pSer42
Latest Publications for our LEF1 抗体
: "Differential Wnt/β-catenin signaling via TCF7L2/LEF1 binding specificity shapes cellular and tumor phenotypes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 123, Issue 24, pp. e2528450123, (2026) (PubMed).
: "Wnt signaling activation induces CTCF binding and loop formation at cis-regulatory elements of target genes." in: Genome research, Vol. 35, Issue 8, pp. 1701-1716, (2025) (PubMed).
: "38" in: , Vol. 1363, Issue Nucleic acids research, pp. 28-39, (1991)
: "A new cut&run low volume-urea (LoV-U) protocol optimized for transcriptional co-factors uncovers Wnt/b-catenin tissue-specific genomic targets." in: Development (Cambridge, England), (2022) (PubMed).
: "Proteome Profile and Quantitative Proteomic Analysis of Buffalo (Bubalusbubalis) Follicular Fluid during Follicle Development." in: International journal of molecular sciences, Vol. 17, Issue 5, (2016) (PubMed).
: "Resveratrol Attenuates Hyperoxia-induced Oxidative Stress, Inflammation and Fibrosis and Suppresses Wnt/?-catenin Signaling in Lungs of Neonatal Rats." in: Clinical and experimental pharmacology & physiology, (2015) (PubMed).
: "MiR-27a regulates Wnt/beta-catenin signaling through targeting SFRP1 in glioma." in: Neuroreport, Vol. 26, Issue 12, pp. 695-702, (2015) (PubMed).
: "Methylprednisolone suppresses the Wnt signaling pathway in chronic lymphocytic leukemia cell line MEC-1 regulated by LEF-1 expression." in: International journal of clinical and experimental pathology, Vol. 8, Issue 7, pp. 7921-8, (2015) (PubMed).
: "The Regenerating Spinal Cord of Gecko Maintains Unaltered Expression of ?-Catenin Following Tail Amputation." in: Journal of molecular neuroscience : MN, (2014) (PubMed).
: "Regulation of ?-catenin nuclear dynamics by GSK-3? involves a LEF-1 positive feedback loop." in: Traffic (Copenhagen, Denmark), Vol. 12, Issue 8, pp. 983-99, (2011) (PubMed).
: "Wnt signaling activation induces CTCF binding and loop formation at cis-regulatory elements of target genes." in: Genome research, Vol. 35, Issue 8, pp. 1701-1716, (2025) (PubMed).
: "38" in: , Vol. 1363, Issue Nucleic acids research, pp. 28-39, (1991)
: "A new cut&run low volume-urea (LoV-U) protocol optimized for transcriptional co-factors uncovers Wnt/b-catenin tissue-specific genomic targets." in: Development (Cambridge, England), (2022) (PubMed).
: "Proteome Profile and Quantitative Proteomic Analysis of Buffalo (Bubalusbubalis) Follicular Fluid during Follicle Development." in: International journal of molecular sciences, Vol. 17, Issue 5, (2016) (PubMed).
: "Resveratrol Attenuates Hyperoxia-induced Oxidative Stress, Inflammation and Fibrosis and Suppresses Wnt/?-catenin Signaling in Lungs of Neonatal Rats." in: Clinical and experimental pharmacology & physiology, (2015) (PubMed).
: "MiR-27a regulates Wnt/beta-catenin signaling through targeting SFRP1 in glioma." in: Neuroreport, Vol. 26, Issue 12, pp. 695-702, (2015) (PubMed).
: "Methylprednisolone suppresses the Wnt signaling pathway in chronic lymphocytic leukemia cell line MEC-1 regulated by LEF-1 expression." in: International journal of clinical and experimental pathology, Vol. 8, Issue 7, pp. 7921-8, (2015) (PubMed).
: "The Regenerating Spinal Cord of Gecko Maintains Unaltered Expression of ?-Catenin Following Tail Amputation." in: Journal of molecular neuroscience : MN, (2014) (PubMed).
: "Regulation of ?-catenin nuclear dynamics by GSK-3? involves a LEF-1 positive feedback loop." in: Traffic (Copenhagen, Denmark), Vol. 12, Issue 8, pp. 983-99, (2011) (PubMed).
Aliases for LEF1 抗体
lymphoid enhancer binding factor 1 (LEF1) 抗体lymphoid enhancer binding factor 1 (lef1) 抗体
lymphoid enhancer-binding factor 1 (lef1) 抗体
lymphoid enhancer binding factor 1 (Lef1) 抗体
lymphoid enhancer factor XLEF-1B (lef1) 抗体
3000002B05 抗体
AI451430 抗体
Lef-1 抗体
LEF-1 抗体
LEF1 抗体
TCF1ALPHA 抗体
TCF7L3 抗体
TCF10 抗体
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