电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

LEF1 抗体 (AA 10-37)

LEF1 适用: 人 WB 宿主: 小鼠 Monoclonal 661CT8-3-5 unconjugated
产品编号 ABIN1882259
发货至: 中国
  • 抗原 See all LEF1 抗体
    LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
    抗原表位
    • 11
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 10-37
    适用
    • 80
    • 20
    • 13
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 53
    • 23
    • 4
    • 1
    小鼠
    克隆类型
    • 55
    • 26
    单克隆
    标记
    • 61
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LEF1 antibody is un-conjugated
    应用范围
    • 68
    • 35
    • 13
    • 11
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    M, Rat
    纯化方法
    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
    免疫原
    This LEF1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 10-37 amino acids from human LEF1.
    克隆位点
    661CT8-3-5
    亚型
    IgG1
  • 应用备注
    WB: 1:500~8000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Gutierrez, Tschumper, Wu, Shanafelt, Eckel-Passow, Huddleston, Slager, Kay, Jelinek: "LEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosis." in: Blood, Vol. 116, Issue 16, pp. 2975-83, (2010) (PubMed).

    Kalsi, Kuo, Aliev, Alexander, McMichael, Patterson, Walsh, Zhao, Schuckit, Nurnberger, Edenberg, Kramer, Hesselbrock, Tischfield, Vladimirov, Prescott, Dick, Kendler, Riley: "A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts." in: Human molecular genetics, Vol. 19, Issue 12, pp. 2497-506, (2010) (PubMed).

    Chen, Zhang, Pincus, Wu, Ricks, Liu, Sun, Maclaren, Lan: "Human CD1D gene expression is regulated by LEF-1 through distal promoter regulatory elements." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 9, pp. 5047-54, (2010) (PubMed).

  • 抗原
    LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
    别名
    LEF1 (LEF1 产品)
    别名
    LEF1 antibody, 3000002B05 antibody, AI451430 antibody, Lef-1 antibody, LEF-1 antibody, TCF10 antibody, TCF1ALPHA antibody, TCF7L3 antibody, lymphoid enhancer binding factor 1 antibody, lymphoid enhancer-binding factor 1 antibody, lymphoid enhancer factor XLEF-1B antibody, LEF1 antibody, lef1 antibody, Lef1 antibody
    背景
    This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
    分子量
    44201
    NCBI登录号
    NP_001124185, NP_001124186, NP_001159591, NP_057353
    UniProt
    Q9UJU2
    途径
    WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding
You are here:
客服