KPNA2 抗体 (C-Term)
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- 抗原 See all KPNA2 抗体
- KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This KPNA2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 序列
- C-QVQDGAPGTF NF
- 特异性
- This antibody detects Importin subunit alpha-2 at C-term.
- 交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat, Canine (Dog).
Species reactivity (tested):Human. - 纯化方法
- Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
- 免疫原
- Peptide from C Terminus of the protein sequence according to NP_002257.1 Genename: KPNA2
- Top Product
- Discover our top product KPNA2 Primary Antibody
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anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (AA 1-530) antibody
KPNA2 适用: 人, 小鼠 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1E8B7 unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (AA 2-285) antibodyKPNA2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (C-Term) antibodyVerified KPNA2 适用: 人, 大鼠 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (AA 1-290) antibodyKPNA2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (C-Term) antibodyKPNA2 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (AA 157-412) antibodyKPNA2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (AA 157-412) antibodyKPNA2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C18 unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) antibodyKPNA2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (AA 420-528) antibodyKPNA2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) antibodyKPNA2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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- 应用备注
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Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.1-0.5 μg/mL. Approx 55-60 kDa band observed in Hela lysates (predictedsize of approx.50 kDa according to NP_002257.1). Immunofluoresence: in 4 % formaldahyde-fixed HeLa staining is mostly cytoplasmic, withsome nuclear staining and clear nuclear pore staining.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
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- 抗原
- KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
- 别名
- KPNA2 / Importin alpha-2 (KPNA2 产品)
- 别名
- IPOA1 antibody, QIP2 antibody, RCH1 antibody, SRP1alpha antibody, ima2 antibody, importin antibody, 2410044B12Rik antibody, PTAC58 antibody, Rch1 antibody, ipoa1 antibody, kpna2 antibody, qip2 antibody, rch1 antibody, srp1alpha antibody, hm:zeh0389 antibody, hm:zeh0389r antibody, zgc:113902 antibody, zgc:86945 antibody, karyopherin subunit alpha 2 antibody, importin subunit alpha-2 antibody, Importin subunit alpha-2 antibody, karyopherin (importin) alpha 2 antibody, karyopherin alpha-2 subunit like L homeolog antibody, karyopherin alpha 2 (RAG cohort 1, importin alpha 1) antibody, KPNA2 antibody, EDI_246290 antibody, EDI_335040 antibody, ima2 antibody, Kpna2 antibody, kpna2.L antibody, kpna2 antibody
- 背景
- The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy independent docking of the protein to the nuclear envelope and the second is an energy dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination.Synonyms: Karyopherin alpha-2, RAG cohort protein 1, RCH1, SRP1-alpha
- 基因ID
- 3838
- NCBI登录号
- NP_002257
- UniProt
- P52292
- 途径
- M Phase, Protein targeting to Nucleus
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