电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

KPNA2 抗体 (AA 1-290)

KPNA2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3022267
发货至: 中国
  • 抗原 See all KPNA2 抗体
    KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
    抗原表位
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-290
    适用
    • 48
    • 25
    • 23
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 33
    • 8
    • 3
    • 2
    • 2
    克隆类型
    • 31
    • 17
    多克隆
    标记
    • 29
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This KPNA2 antibody is un-conjugated
    应用范围
    • 28
    • 10
    • 9
    • 8
    • 8
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    序列
    MSTNENANTP AARLHRFKNK GKDSTEMRRR RIEVNVELRK AKKDDQMLKR RNVSSFPDDA TSPLQENRNN QGTVNWSVDD IVKGINSSNV ENQLQATQAA RKLLSREKQP PIDNIIRAGL IPKFVSFLGR TDCSPIQFES AWALTNIASG TSEQTKAVVD GGAIPAFISL LASPHAHISE QAVWALGNIA GDGSVFRDLV IKYGAVDPLL ALLAVPDMSS LACGYLRNLT WTLSNLCRNK NPAPPIDAVE QILPTLVRLL HHDDPEVLAD TCWAISYLTD GPNERIGMVV
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human KPNA2 (NP_002257.1).
    亚型
    IgG
    Top Product
    Discover our top product KPNA2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IP,1:50 - 1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Ye, Chen, Li, Zhao, He, Zohaib, Song, Deng, Zhang, Chen, Cao: "Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB." in: Journal of virology, Vol. 91, Issue 8, (2017) (PubMed).

  • 抗原
    KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
    别名
    KPNA2 (KPNA2 产品)
    别名
    IPOA1 antibody, QIP2 antibody, RCH1 antibody, SRP1alpha antibody, ima2 antibody, importin antibody, 2410044B12Rik antibody, PTAC58 antibody, Rch1 antibody, ipoa1 antibody, kpna2 antibody, qip2 antibody, rch1 antibody, srp1alpha antibody, hm:zeh0389 antibody, hm:zeh0389r antibody, zgc:113902 antibody, zgc:86945 antibody, karyopherin subunit alpha 2 antibody, importin subunit alpha-2 antibody, Importin subunit alpha-2 antibody, karyopherin (importin) alpha 2 antibody, karyopherin alpha-2 subunit like L homeolog antibody, karyopherin alpha 2 (RAG cohort 1, importin alpha 1) antibody, KPNA2 antibody, EDI_246290 antibody, EDI_335040 antibody, ima2 antibody, Kpna2 antibody, kpna2.L antibody, kpna2 antibody
    背景
    The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. Alternative splicing results in multiple transcript variants.,KPNA2,IPOA1,QIP2,RCH1,SRP1-alpha,SRP1alpha,Signal Transduction,Immunology & Inflammation,KPNA2
    分子量
    57 kDa
    基因ID
    3838
    UniProt
    P52292
    途径
    M Phase, Protein targeting to Nucleus
You are here:
客服