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KPNA2 抗体 (AA 2-285)

This 兔 多克隆 antibody specifically detects KPNA2 in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 人.
产品编号 ABIN7156118
发货至: 中国
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Quick Overview for KPNA2 抗体 (AA 2-285) (ABIN7156118)

抗原

See all KPNA2 抗体
KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))

适用

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宿主

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克隆类型

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多克隆

标记

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This KPNA2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 2-285

    原理

    KPNA2 Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Importin subunit alpha-1 protein (2-285AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))

    别名

    KPNA2

    背景

    Background: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.

    Aliases: IMA1_HUMAN antibody, Importin alpha 1 antibody, Importin alpha 2 antibody, Importin alpha 2 subunit antibody, Importin alpha P1 antibody, Importin subunit alpha-1 antibody, IPO A1 antibody, IPOA 1 antibody, IPOA1 antibody, Karyopherin alpha 2 antibody, Karyopherin alpha 2 RAG cohort 1 antibody, Karyopherin alpha 2 subunit antibody, Karyopherin subunit alpha-2 antibody, KPNA2 antibody, KPNA2 protein antibody, Pendulin antibody, QIP 2 antibody, QIP2 antibody, RAG cohort 1 antibody, RAG cohort protein 1 antibody, RCH 1 antibody, RCH1 antibody, SRP 1 antibody, SRP1 alpha antibody, SRP1 antibody, SRP1-alpha antibody, SRP1alpha antibody

    UniProt

    P52292

    途径

    M Phase, Protein targeting to Nucleus
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