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ISG15 抗体 (Middle Region)

ISG15 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN356681
发货至: 中国
  • 抗原 See all ISG15 抗体
    ISG15 (ISG15 Ubiquitin-Like Modifier (ISG15))
    抗原表位
    • 10
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 59
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 55
    • 5
    • 1
    克隆类型
    • 54
    • 7
    多克隆
    标记
    • 38
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ISG15 antibody is un-conjugated
    应用范围
    • 47
    • 30
    • 27
    • 10
    • 7
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody is specific to ISG15 (Center).
    纯化方法
    Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human ISG15.
    亚型
    Ig Fraction
    Top Product
    Discover our top product ISG15 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blot: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS containing 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    ISG15 (ISG15 Ubiquitin-Like Modifier (ISG15))
    别名
    ISG15 / G1P2 (ISG15 产品)
    别名
    G1P2 antibody, IFI15 antibody, IP17 antibody, UCRP antibody, hUCRP antibody, ISG15 antibody, g1p2 antibody, si:rp71-1c23.2 antibody, G1p2 antibody, IGI15 antibody, Irfp antibody, ISG17 antibody, ISG17/UCRP antibody, ISG15 ubiquitin-like modifier antibody, ISG15 antibody, isg15 antibody, Isg15 antibody
    背景
    ISG15 is secreted from monocytes in response to type I interferons and causes natural killer (NK)-cell proliferation and an augmentation of non-MCH (major histocompatibility complex)-restricted cytotoxicity. Synthesis is stimulated by IFN-alpha or IFN-beta or IFN-omega , but not IFN-gamma . ISG15 expression is also induced by overexpression of interferon regulatory factors that participate in transcriptional regulation of IFN genes, and by influenza B virus. ISG15 is secreted also by cell lines of monocyte, T-lymphocyte, B-lymphocyte, human fibroblasts, and epithelial origins. The induction of terminal differentiation in human melanoma cells is associated with alterations in ISG15 expression. Enhancement of NK cell proliferation, augmentation of non-major histocompatibility complex-restricted cytotoxicity, and induction of IFN-gamma from T cells identify ISG15 as a member of the cytokine cascade and suggest that it may be responsible for amplifying and directing some of the immunomodulatory effects of IFN-alpha or IFN-beta. ISG15 has has also been shown to function intracellularly as a ubiquitin homolog.Synonyms: Interferon-induced 15 kDa protein, Interferon-induced 17 kDa protein, UCRP, Ubiquitin cross-reactive protein
    基因ID
    9636, 9606
    UniProt
    P05161
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