ISG15 抗体 (N-Term)
(5 references)-
- 抗原 See all ISG15 抗体
- ISG15 (ISG15 Ubiquitin-Like Modifier (ISG15))
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抗原表位
- AA 31-61, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ISG15 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This ISG15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-61 amino acids from the N-terminal region of human ISG15.
- 克隆位点
- RB02791
- 亚型
- Ig Fraction
- Top Product
- Discover our top product ISG15 Primary Antibody
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anti-ISG15 Ubiquitin-Like Modifier (ISG15) (AA 2-157) antibody
ISG15 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (AA 1-165) antibodyISG15 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (AA 1-165) antibodyISG15 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (Middle Region) antibodyISG15 适用: 人, 马, Pig, 兔, 绵羊, Cow, 犬, 山羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (AA 31-61) antibodyISG15 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) antibodyISG15 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (AA 39-68), (N-Term) antibodyISG15 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) antibodyISG15 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (C-Term) antibodyISG15 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ISG15 Ubiquitin-Like Modifier (ISG15) (AA 80-129) antibodyISG15 适用: 人, 马, Pig, 兔, 绵羊, Cow, 犬 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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: "ISG15 induction is required during L1-mediated colon cancer progression and metastasis." in: Oncotarget, Vol. 10, Issue 67, pp. 7122-7131, (2019) (PubMed).
: "ISG15 deficiency and increased viral resistance in humans but not mice. ..." in: Nature communications, Vol. 7, pp. 11496, (2018) (PubMed).
: "Herpes simplex virus and interferon signaling induce novel autophagic clusters in sensory neurons." in: Journal of virology, (2016) (PubMed).
: "Oncogene-mediated regulation of p53 ISGylation and functions." in: Oncotarget, Vol. 5, Issue 14, pp. 5808-18, (2015) (PubMed).
: "Interferon stimulated gene 15 expression at the human embryo-maternal interface." in: Archives of gynecology and obstetrics, Vol. 290, Issue 4, pp. 783-9, (2014) (PubMed).
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: "ISG15 induction is required during L1-mediated colon cancer progression and metastasis." in: Oncotarget, Vol. 10, Issue 67, pp. 7122-7131, (2019) (PubMed).
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- 抗原
- ISG15 (ISG15 Ubiquitin-Like Modifier (ISG15))
- 别名
- ISG15 (ISG15 产品)
- 别名
- G1P2 antibody, IFI15 antibody, IP17 antibody, UCRP antibody, hUCRP antibody, ISG15 antibody, g1p2 antibody, si:rp71-1c23.2 antibody, G1p2 antibody, IGI15 antibody, Irfp antibody, ISG17 antibody, ISG17/UCRP antibody, ISG15 ubiquitin-like modifier antibody, ISG15 antibody, isg15 antibody, Isg15 antibody
- 背景
- ISG15 is secreted from monocytes in response to type I interferons and causes natural killer (NK)-cell proliferation and an augmentation of non-MCH (major histocompatibility complex)-restricted cytotoxicity. Synthesis is stimulated by IFN-alpha or IFN-beta or IFN-omega , but not IFN-gamma . ISG15 expression is also induced by overexpression of interferon regulatory factors that participate in transcriptional regulation of IFN genes, and by influenza B virus. ISG15 is secreted also by cell lines of monocyte, T-lymphocyte, B-lymphocyte, human fibroblasts, and epithelial origins. The induction of terminal differentiation in human melanoma cells is associated with alterations in ISG15 expression. Enhancement of NK cell proliferation, augmentation of non-major histocompatibility complex-restricted cytotoxicity, and induction of IFN-gamma from T cells identify ISG15 as a member of the cytokine cascade and suggest that it may be responsible for amplifying and directing some of the immunomodulatory effects of IFN-alpha or IFN-beta. ISG15 has has also been shown to function intracellularly as a ubiquitin homolog.
- 分子量
- 17888
- 基因ID
- 9636
- NCBI登录号
- NP_005092
- UniProt
- P05161
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