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CHEK1 抗体

The 小鼠 单克隆 anti-CHEK1 antibody (Clone 2G1D5) (ABIN3209997) specifically detects CHEK1 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN3209997
发货至: 中国
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Quick Overview for CHEK1 抗体 (ABIN3209997)

抗原

See all CHEK1 抗体
CHEK1 (Checkpoint Kinase 1 (CHEK1))

适用

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人, 小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CHEK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

2G1D5
  • 交叉反应

    小鼠

    纯化方法

    Purified antibody.

    免疫原

    CHK1 antibody was raised in Mouse using a purified recombinant fragment of CHK1 expressed in E. coli as the immunogen.

    亚型

    IgG1
  • 应用备注

    ELISA: 1:10,000, WB: 1:500-1:2,000
    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    Lot specific

    缓冲液

    Purified antibody supplied in PBS containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C for short term storage. Store at -20 °C for long term storage.
  • 抗原

    CHEK1 (Checkpoint Kinase 1 (CHEK1))

    别名

    CHK1

    背景

    CHK1 is a kinase that phosphorylates Cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Cdc25, when phosphorylated on serine 216 by chk1 becomes bound by an adaptor protein in the cytoplasm. Therefore it is inhibited from removing the inhibiting phosphate from MPF (mitotic/maturation promoting factor) added by Wee1. Consequently, a cell is prevented from entering mitosis. Synonyms: Monoclonal CHK1 antibody, Anti-CHK1 antibody, CHK-1 antibody, CHK 1 antibody, CHEK1 antibody.

    途径

    p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
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