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MAPK14 抗体 (pThr180, pTyr182)

MAPK14 适用: 人, 小鼠, 大鼠, 犬, 小鸡, Cow, 猴, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN319104
发货至: 中国
  • 抗原 See all MAPK14 抗体
    MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))
    抗原表位
    • 34
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    pThr180, pTyr182
    适用
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    人, 小鼠, 大鼠, 犬, 小鸡, Cow, 猴, 斑马鱼
    宿主
    • 207
    • 32
    • 2
    • 1
    克隆类型
    • 199
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    多克隆
    标记
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    This MAPK14 antibody is un-conjugated
    应用范围
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    Western Blotting (WB)
    特异性
    This antibody is specific for p38 mitogen-activated protein kinase (p38 MAPK), also known as MAPK14, when phosphorylated at Threonine 180 and Tyrosine 182.
    交叉反应 (详细)
    Species reactivity (expected):Chicken, Zebrafish, Bovine, Monkey, Mouse and Canine (Dog).
    Species reactivity (tested):Human and Rat.
    纯化方法
    Affinity Chromatography.
    免疫原
    Synthetic phosphopeptide corresponding to an amino acid sequence within p38 MAPK which includes phosphorylated Thr180 and Tyr182.
    亚型
    IgG
    Top Product
    Discover our top product MAPK14 Primary Antibody
  • 应用备注
    Western Blot: 1/1000. This p38 MAPK antibody Recognises a band of approximately 39 kD in Western blots ofanisomycin C-6 glioma cell lysates. For the detection of phosphoproteins, Threonine and Tyrosine phosphatase inhibitors suchas 10 mM Sodium Fluoride and 1 mM Sodium Orthovanadate should be added to the samplebuffer. Milk or other casein-based blocking solutions are not recommended as casein is aphosphoprotein and its use can result in high background.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM HEPES, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % BSA and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))
    别名
    MAP Kinase p38 alpha / MAPK14 (MAPK14 产品)
    别名
    CSBP antibody, CSBP1 antibody, CSBP2 antibody, CSPB1 antibody, EXIP antibody, Mxi2 antibody, PRKM14 antibody, PRKM15 antibody, RK antibody, SAPK2A antibody, p38 antibody, p38ALPHA antibody, CRK1 antibody, Csbp1 antibody, Csbp2 antibody, Exip antibody, Hog antibody, Prkm14 antibody, Prkm15 antibody, Sapk2A antibody, p38Hog antibody, p38alpha antibody, p38b antibody, zp38b antibody, MAPK14 antibody, 186F5S antibody, BG:DS00797.3 antibody, CG7393 antibody, D-p38 antibody, D-p38 MAPK antibody, D-p38b antibody, Dm p38b antibody, Dmel\\CG7393 antibody, Dmp38b antibody, Dp38 antibody, Dp38b antibody, ESTS:186F5S antibody, Mpk34C antibody, anon-sts23 antibody, dp38b antibody, p38 MAPK antibody, p38 beta antibody, p38B antibody, p38Kb antibody, p38beta antibody, Crk1 antibody, p38-alpha antibody, p38MAPK antibody, p38a antibody, csbp antibody, mapk14a antibody, mxi2 antibody, sapk2 antibody, sapk2a antibody, AP22.98 antibody, AP22_98 antibody, ATMPK14 antibody, mitogen-activated protein kinase 14 antibody, SAPK2a antibody, MAP kinase 14A antibody, MAP kinase p38a antibody, MAPK 14A antibody, fk28c03 antibody, hm:zeh1243 antibody, wu:fk28c03 antibody, zp38a antibody, P38C-CRK antibody, mitogen-activated protein kinase 14 antibody, mitogen activated protein kinase 14 antibody, mitogen-activated protein kinase 14b antibody, p38b MAP kinase antibody, mitogen-activated protein kinase 14 S homeolog antibody, mitogen-activated protein kinase 14a antibody, CRK proto-oncogene, adaptor protein antibody, MAPK14 antibody, Mapk14 antibody, mapk14b antibody, p38b antibody, mapk14.S antibody, MPK14 antibody, mapk14a antibody, CRK antibody
    背景
    P38 MAPK is a serine/threonine kinase which plays an important role in signal transduction, contributing to the regulation of many cellular processes including cell differentiation and inflammation. The protein is activated by phosphorylation of threonine 180 and tyrosine 182, by several upstream kinases, in response to a wide range of extracellular stimuli such as UV B irradiation or endotoxin exposure.Synonyms: CSBP, CSBP1, CSBP2, CSPB1, Cytokine suppressive anti-inflammatory drug-binding protein, MAX-interacting protein 2, MXI2, Mitogen-activated protein kinase 14, SAPK2A, p38 alpha
    基因ID
    1432
    NCBI登录号
    NP_001306
    UniProt
    Q16539
    途径
    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins
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