MAPK14 产品
(Mitogen-Activated Protein Kinase 14 (MAPK14))
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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
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Featured MAPK14 Categories
MAPK14 抗体
High quality antibodies with extensive validation data.
MAPK14 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
MAPK14 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MAPK14 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Chicken, Goat, Human, Mouse, Rat
Application
WB, ELISA, IHC (p), FACS, IF (cc)
Validations
- (3)
- (3)
- (1)
Cat. No.
ABIN678668
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (2)
- (8)
Cat. No.
ABIN1724830
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rabbit, Rat
Application
WB, ELISA, IHC (p), FACS, ICC, IF (cc), IF (p), IHC (fro)
Validations
- (17)
- (4)
Cat. No.
ABIN671241
Quantity
100 μL
Datasheet
Datasheet
Recommended MAPK14 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Cell ELISA
Validations
- (4)
- (6)
Cat. No.
ABIN1981835
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (1)
- (5)
Cat. No.
ABIN625242
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (2)
- (4)
Cat. No.
ABIN625229
Quantity
96 tests
Datasheet
Datasheet
Recommended MAPK14 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
Cat. No.
ABIN5570140
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
Cat. No.
ABIN5570141
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
Cat. No.
ABIN5570497
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MAPK14 Products
: "The Histone Deacetylase Inhibitor (MS-275) Promotes Differentiation of Human Dental Pulp Stem Cells into Odontoblast-Like Cells Independent of the MAPK Signaling System." in: International journal of molecular sciences, Vol. 21, Issue 16, (2021) (PubMed).: "PSMD1 and PSMD2 regulate HepG2 cell proliferation and apoptosis via modulating cellular lipid droplet metabolism." in: BMC molecular biology, Vol. 20, Issue 1, pp. 24, (2020) (PubMed).
: "Perilipin 5 Protects against Cellular Oxidative Stress by Enhancing Mitochondrial Function in HepG2 Cells." in: Cells, Vol. 8, Issue 10, (2020) (PubMed).
: "EGF receptor and PKCδ kinase activate DNA damage-induced pro-survival and pro-apoptotic signaling via biphasic activation of ERK and MSK1 kinases." in: The Journal of biological chemistry, Vol. 294, Issue 12, pp. 4488-4497, (2019) (PubMed).
: "Nonylphenol attenuates SOCS3 expression and M1 polarization in lipopolysaccharide-treated rat splenic macrophages." in: Ecotoxicology and environmental safety, Vol. 174, pp. 574-583, (2019) (PubMed).
: "Toll-like receptor 3-mediated inflammation by p38 is enhanced by endothelial nitric oxide synthase knockdown." in: Cell communication and signaling : CCS, Vol. 17, Issue 1, pp. 33, (2019) (PubMed).
: "Exenatide ameliorates inflammatory response in human rheumatoid arthritis fibroblast-like synoviocytes." in: IUBMB life, Vol. 71, Issue 7, pp. 969-977, (2019) (PubMed).
: "Modeling G2019S-LRRK2 Sporadic Parkinson's Disease in 3D Midbrain Organoids." in: Stem cell reports, Vol. 12, Issue 3, pp. 518-531, (2019) (PubMed).
: "Tumor Necrosis Factor-α-Mediated Metaplastic Inhibition of LTP Is Constitutively Engaged in an Alzheimer's Disease Model." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 39, Issue 46, pp. 9083-9097, (2019) (PubMed).
: "MicroRNA-124 regulates the expression of p62/p38 and promotes autophagy in the inflammatory pathogenesis of Parkinson's disease." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 7, pp. 8648-8665, (2019) (PubMed).
Synonyms and alternative names related to MAPK14
mitogen-activated protein kinase 14 (MAPK14), mitogen activated protein kinase 14 (Mapk14), mitogen-activated protein kinase 14b (mapk14b), p38b MAP kinase (p38b), mitogen-activated protein kinase 14 (Mapk14), mitogen-activated protein kinase 14 S homeolog (mapk14.S), mitogen-activated protein kinase 14 (MPK14), mitogen-activated protein kinase 14a (mapk14a), CRK proto-oncogene, adaptor protein (CRK), 186F5S, anon-sts23, AP22.98, AP22_98, ATMPK14, BG:DS00797.3, CG7393, CRK1, Crk1, CSBP, csbp, CSBP1, Csbp1, CSBP2, Csbp2, CSPB1, D-p38, D-p38 MAPK, D-p38b, Dmel\\CG7393, Dm p38b, Dmp38b, Dp38, Dp38b, dp38b, ESTS:186F5S, EXIP, Exip, fk28c03, hm:zeh1243, Hog, MAPK14, mapk14a, MAPK 14A, MAP kinase 14A, MAP kinase p38a, mitogen-activated protein kinase 14, Mpk34C, Mxi2, mxi2, p38, p38 beta, p38 MAPK, p38-alpha, p38a, p38ALPHA, p38alpha, p38b, p38B, p38beta, P38C-CRK, p38Hog, p38Kb, p38MAPK, PRKM14, Prkm14, PRKM15, Prkm15, RK, sapk2, SAPK2A, Sapk2A, sapk2a, SAPK2a, wu:fk28c03, zp38a, zp38bProtein level used designations for MAPK14
- Csaids binding protein
- MAP kinase 14
- MAP kinase 2
- MAP kinase Mxi2
- MAP kinase p38 alpha
- MAPK 14
- MAX-interacting protein 2
- cytokine suppressive anti-inflammatory drug binding protein
- cytokine-supressive anti-inflammatory drug binding protein
- mitogen-activated protein kinase 14
- mitogen-activated protein kinase 14A
- mitogen-activated protein kinase p38 alpha
- p38 MAP kinase
- p38 mitogen activated protein kinase
- p38alpha Exip
- reactive kinase
- stress-activated protein kinase 2A
- MAP kinase 14B
- MAP kinase p38b
- MAPK 14B
- mitogen-activated protein kinase 14B
- mitogen-activated protein kinase p38b
- CG7393-PA
- p38 mitogen-activated protein kinase
- p38b-PA
- stress-activated p38b MAP kinase
- cytokine suppressive anti-inflammatory drug binding protein 1
- mitogen activated protein kinase 14
- p38 MAP kinase alpha
- p38 MAPK
- p38 alpha
- tRNA synthetase cofactor p38
- MAPK p38
- MPK2
- Mitogen-activated protein kinase 2
- mitogen-activated Mitogen-activated protein kinase 2
- p38 mitogen-activated kinase
- CSAIDS-binding protein 1
- stress-activated protein kinase 2a
- MAP kinase 14A
- MAP kinase p38a
- MAPK 14A
- Mitogen-activated protein kinase p38a
- etID18993.8
- mitogen-activated protein kinase p38a
- zeh1243
- CRK proto-oncogene, adaptor protein
- Proto-oncogene c-Crk
- adapter molecule crk
- p38
- proto-oncogene C-crk
- v-crk avian sarcoma virus CT10 oncogene homolog
- v-crk sarcoma virus CT10 oncogene homolog
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