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MAPKAP1 产品

(Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))
This gene encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alternate 3' UTRs have been identified for transcripts of this gene. [provided by RefSeq, Jul 2008].

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Featured MAPKAP1 Categories

MAPKAP1 抗体

High quality antibodies with extensive validation data.

MAPKAP1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

MAPKAP1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MAPKAP1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7445810
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Human, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN960906
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN7268632
Quantity 100 μL
Datasheet Datasheet

Recommended MAPKAP1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957864
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1160834
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1160835
Quantity 96 tests
Datasheet Datasheet

Recommended MAPKAP1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310321
Quantity 2 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310319
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3095456
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MAPKAP1 Products

Hau, Gupta, Leivo, Nakashima, Macias, Zhou, Hodge, Wulfkuhle, Conkright, Bhuvaneshwar, Rao, Madhavan, Petricoin, Hansel: "Dynamic Regulation of Caveolin-1 Phosphorylation and Caveolae Formation by Mammalian Target of Rapamycin Complex 2 in Bladder Cancer Cells." in: The American journal of pathology, Vol. 189, Issue 9, pp. 1846-1862, (2019) (PubMed).

Cameron, Veeriah, Marshall, Murray, Larijani, Parker: "Uncoupling TORC2 from AGC kinases inhibits tumour growth." in: Oncotarget, Vol. 8, Issue 49, pp. 84685-84696, (2017) (PubMed).

Misra, Pizzo: "Upregulation of mTORC2 activation by the selective agonist of EPAC, 8-CPT-2Me-cAMP, in prostate cancer cells: assembly of a multiprotein signaling complex." in: Journal of cellular biochemistry, Vol. 113, Issue 5, pp. 1488-500, (2012) (PubMed).

Das, Ghosh-Choudhury, Dey, Mandal, Mahimainathan, Kasinath, Abboud, Choudhury: "Unrestrained mammalian target of rapamycin complexes 1 and 2 increase expression of phosphatase and tensin homolog deleted on chromosome 10 to regulate phosphorylation of Akt kinase." in: The Journal of biological chemistry, Vol. 287, Issue 6, pp. 3808-22, (2012) (PubMed).

Lu, Wang, Ives, Pearce: "mSIN1 protein mediates SGK1 protein interaction with mTORC2 protein complex and is required for selective activation of the epithelial sodium channel." in: The Journal of biological chemistry, Vol. 286, Issue 35, pp. 30647-54, (2011) (PubMed).

Huang, Wu, Wu, Manning: "Signaling events downstream of mammalian target of rapamycin complex 2 are attenuated in cells and tumors deficient for the tuberous sclerosis complex tumor suppressors." in: Cancer research, Vol. 69, Issue 15, pp. 6107-14, (2009) (PubMed).

Jacinto, Facchinetti, Liu, Soto, Wei, Jung, Huang, Qin, Su: "SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity." in: Cell, Vol. 127, Issue 1, pp. 125-37, (2006) (PubMed).

Wullschleger, Loewith, Hall: "TOR signaling in growth and metabolism." in: Cell, Vol. 124, Issue 3, pp. 471-84, (2006) (PubMed).

Cheng, Zhang, Kim, Zhao, Zhao, Su: "Mip1, an MEKK2-interacting protein, controls MEKK2 dimerization and activation." in: Molecular and cellular biology, Vol. 25, Issue 14, pp. 5955-64, (2005) (PubMed).

Schroder, Cloonan, Bushell, Sculley: "Alternative polyadenylation and splicing of mRNAs transcribed from the human Sin1 gene." in: Gene, Vol. 339, pp. 17-23, (2004) (PubMed).

Synonyms and alternative names related to MAPKAP1

SAPK-interacting protein 1 (Sin1), mitogen-activated protein kinase associated protein 1 (MAPKAP1), mitogen-activated protein kinase associated protein 1 (mapkap1), mitogen-activated protein kinase associated protein 1 (Mapkap1), mitogen-activated protein kinase associated protein 1 L homeolog (mapkap1.L), AI591529, CG10105, D230039K05Rik, Dmel\\CG10105, dSin1, im:7143088, JC310, MAPKAP1, MGC53034, mip1, MIP1, si:ch73-242f23.1, sin1, SIN1, Sin1, sin1b, SIN1b, sin1g, SIN1g

Protein level used designations for MAPKAP1

  • CG10105-PA
  • Sin1-PA
  • Stress-activated protein kinase [SAPK]-interacting protein
  • stress-activated map kinase-interacting protein 1
  • mitogen-activated protein kinase associated protein 1
  • Target of rapamycin complex 2 subunit MAPKAP1
  • target of rapamycin complex 2 subunit MAPKAP1-like
  • MEKK2-interacting protein 1
  • SAPK-interacting protein 1
  • TORC2 subunit MAPKAP1
  • mSIN1
  • mitogen-activated protein kinase 2-associated protein 1
  • ras inhibitor MGC2745
  • stress-activated map kinase interacting protein 1
  • stress-activated protein kinase-interacting 1
  • target of rapamycin complex 2 subunit MAPKAP1
  • mitogen activated protein kinase associated protein 1
  • SAPK interacting protein
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