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- 抗原 See all UHRF1 抗体
- UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))
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抗原表位
- AA 14-51, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UHRF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase UHRF1(UHRF1) detection. Tested with WB, IHC-P in Human.
- 序列
- HTVDSLSRLT KVEELRRKIQ ELFHVEPGLQ RLFYRGKQ
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase UHRF1(UHRF1) detection. Tested with WB, IHC-P in Human.
Gene Name: ubiquitin-like with PHD and ring finger domains 1
Protein Name: E3 ubiquitin-protein ligase UHRF1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human UHRF1 (14-51aa HTVDSLSRLTKVEELRRKIQELFHVEPGLQRLFYRGKQ), different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product UHRF1 Primary Antibody
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anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 1-260) antibody
UHRF1 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 616-755) antibodyUHRF1 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 1A1B1 unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 694-793) antibodyUHRF1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A11 unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 616-755) antibodyUHRF1 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 2A8C7 unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 229-257) antibodyUHRF1 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (N-Term) antibodyUHRF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) antibodyKO Validated UHRF1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 596-628), (C-Term) antibodyUHRF1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB51453 unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (meLys385) antibodyUHRF1 适用: 人 WB, IHC, DB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) (AA 229-257) antibodyUHRF1 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB21516 unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))
- 别名
- UHRF1 (UHRF1 产品)
- 别名
- ICBP90 antibody, Np95 antibody, RNF106 antibody, hNP95 antibody, hUHRF1 antibody, AL022808 antibody, NP95 antibody, fb97f09 antibody, wu:fb97f09 antibody, zgc:63539 antibody, UHRF1 antibody, ubiquitin like with PHD and ring finger domains 1 antibody, ubiquitin-like, containing PHD and RING finger domains, 1 antibody, ubiquitin-like with PHD and ring finger domains 1 antibody, UHRF1 antibody, Uhrf1 antibody, uhrf1 antibody
- 背景
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Ubiquitin-like, containing PHD and RING finger domains, 1 is a protein which in humans is encoded by the UHRF1 gene. This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12.
Synonyms: Ac2-121 antibody|AL022808 antibody|E3 ubiquitin-protein ligase UHRF1 antibody|EC 6.3.2.- antibody|FLJ21925 antibody|hNP95 antibody| hUHRF1 antibody|HuNp95 antibody|ICBP90 antibody|Inverted CCAAT box binding protein of 90 kDa antibody|Inverted CCAAT box binding protein, 90-kD antibody|Inverted CCAAT box-binding protein of 90 kDa antibody|Liver regeneration-related protein LRRG126 antibody| MGC138707 antibody|NP95 antibody|Nuclear phosphoprotein, 95-KD antibody|Nuclear protein 95 antibody|Nuclear zinc finger protein Np95 antibody|RING finger protein 106 antibody|RNF106 antibody|Transcription factor ICBP90 antibody|Ubiquitin like containing PHD and RING finger domains protein 1 antibody|Ubiquitin like PHD and RING finger domain containing protein 1 antibody|Ubiquitin-like PHD and RING finger domain-containing protein 1 antibody|Ubiquitin-like protein containing PHD and RING finger domains 1 antibody|Ubiquitin-like with PHD and ring finger domains 1 antibody|Ubiquitin-like, containing PHD and RING finger domains, 1 antibody|Ubiquitin-like-containing PHD and RING finger domains protein 1 antibody|UHRF1 antibody|UHRF1_HUMAN antibody - 基因ID
- 29128
- UniProt
- Q96T88
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