UHRF1 抗体 (AA 229-257)
Our Local Distributor
北京 101111
Quick Overview for UHRF1 抗体 (AA 229-257) (ABIN3029440)
抗原
See all UHRF1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 229-257
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 229-257 from the human protein was used as the immunogen for this UHRF1 antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the UHRF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the UHRF1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))
-
别名
- UHRF1
-
背景
- UHRF1 is a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone acetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint.
-
UniProt
- Q96T88
抗原
-