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- 抗原 See all ALOX5 抗体
- ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))
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抗原表位
- AA 650-667, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ALOX5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Arachidonate 5-lipoxygenase(ALOX5) detection. Tested with WB, IHC-P in Human.
- 序列
- AERNKKKQLP YYYLSPDR
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Arachidonate 5-lipoxygenase(ALOX5) detection. Tested with WB, IHC-P in Human.
Gene Name: arachidonate 5-lipoxygenase
Protein Name: Arachidonate 5-lipoxygenase(5-LO/5-lipoxygenase) - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human ALOX5(650-667aa AERNKKKQLPYYYLSPDR), different from the related rat and mouse sequences by two amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ALOX5 Primary Antibody
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anti-Arachidonate 5-Lipoxygenase (ALOX5) (AA 461-671) antibody
ALOX5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase (ALOX5) (AA 1-674) antibodyALOX5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase (ALOX5) (AA 1-300) antibodyALOX5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase (ALOX5) antibodyALOX5 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Arachidonate 5-Lipoxygenase (ALOX5) (AA 120-483) antibodyALOX5 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase (ALOX5) (AA 601-674) antibodyALOX5 适用: 人, 大鼠, 小鼠 IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase (ALOX5) (C-Term) antibodyALOX5 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase (ALOX5) (AA 461-671) antibodyALOX5 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D10 unconjugated
anti-Arachidonate 5-Lipoxygenase (ALOX5) (AA 2-149) antibodyALOX5 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 5-Lipoxygenase (ALOX5) antibodyALOX5 适用: 人, 大鼠, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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- 抗原
- ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))
- 别名
- ALOX5 (ALOX5 产品)
- 别名
- 5-LO antibody, 5-LOX antibody, 5LPG antibody, LOG5 antibody, 5LO antibody, 5LX antibody, AI850497 antibody, F730011J02 antibody, LOX5A antibody, si:dkey-194n13.2 antibody, lox5 antibody, arachidonate 5-lipoxygenase antibody, arachidonate 5-lipoxygenase a antibody, Arachidonate 5-lipoxygenase antibody, ALOX5 antibody, Alox5 antibody, alox5a antibody, AFUA_4G02770 antibody, AOR_1_1362014 antibody, lox5 antibody
- 背景
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ALOX5(ARACHIDONATE 5-LIPOXYGENASE), also known as LOG5 or 5-LO(5-LIPOXYGENASE), is an enzyme that in humans is encoded by the ALOX5 gene. ALOX5 is a member of the lipoxygenase family of enzymes which also transforms EFAs into leukotrienes and is a current target for pharmaceutical intervention in a number of diseases. The enzyme 5-lipoxygenase catalyzes 2 reactions in the formation of leukotrienes. The ALOX5 gene is mapped to chromosome 10q11.21 based on an alignment of the ALOX5 sequence with the genomic sequence. Human 5-LO contains 3 nuclear localization sequences(NLSs) and a phosphorylation site involved in nuclear localization. Compared with age-matched 5-LO competent mice, the 5-LO knockout mice developed less right heart hypertrophy. Pharmacologic inhibition or ALOX5 gene disruption resulted in a significant decrease of beta-amyloid production and gamma-secretase levels. ALOX5 activity is short-lived, apparently in part because of an intrinsic instability of the enzyme.
Synonyms: 5 LO antibody|5 LOX antibody|5-lipoxygenase antibody|5-LO antibody|5-LOX antibody|5LOX antibody|5LPG antibody|ALOX 5 antibody|Alox5 antibody|Arachidonate 5 lipoxygenase antibody|Arachidonate 5-lipoxygenase antibody|arachidonic 5-lipoxygenase alpha-10 isoform antibody|arachidonic 5-lipoxygenase delta-10-13 isoform antibody|arachidonic 5-lipoxygenase delta-13 isoform antibody|arachidonic 5-lipoxygenase delta-p10 isoform antibody|Arachidonic acid 5 lipoxygenase antibody|Leukotriene A4 synthase antibody|LOG 5 antibody|LOG5 antibody|LOX5_HUMAN antibody|MGC163204 antibody - UniProt
- P09917
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